2026年10月7日（星期三）
本日收錄 38 篇文獻AA in Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Nonalcoholic Fatty Liver Disease (NAFLD).
Obesity and MASLD (NAFLD) are chronic, low-grade systemic inflammatory diseases resulting from complex interactions among diet, adipose tissue, gut microbiota, liver, muscle, pancreas, and the brain.
An eHealth-Delivered Total Diet Replacement Intervention for Type 2 Diabetes Remission: Single-Arm Pilot Study.
BACKGROUND: The Diabetes Remission Clinical Trial (DiRECT) demonstrated that remission of type 2 diabetes can be achieved through substantial weight loss using a total diet replacement (TDR) intervent
A Unique Case of Granulomatosis with Polyangiitis Presenting with Proximal Muscle Weakness.
Granulomatosis with polyangiitis (GPA) is a subtype of ANCA-associated vasculitis that can have a heterogeneous clinical presentation. Although classically involving the respiratory tract and kidneys,
Sex-stratified immune patterns across the canine lifespan and short-term responses to geroprotective interventions.
Canine models are invaluable for translational geroscience, but natural sex-associated immune aging remains under investigated. Here, we characterize the age-associated hematologic and serum cytokine
Pediococcus acidilactici ZQ-19 Ameliorates Ulcerative Colitis via Remodeling Gut Microbiota and Glutathione Redox Homeostasis.
Ulcerative colitis (UC) is closely linked to intestinal oxidative stress, gut dysbiosis and selenium metabolism disorders. In this study, 449 lactic acid bacteria strains were isolated from yak yogurt
AA in Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Nonalcoholic Fatty Liver Disease (NAFLD).
Obesity and MASLD (NAFLD) are chronic, low-grade systemic inflammatory diseases resulting from compl
An eHealth-Delivered Total Diet Replacement Intervention for Type 2 Diabetes Remission: Single-Arm Pilot Study.
BACKGROUND: The Diabetes Remission Clinical Trial (DiRECT) demonstrated that remission of type 2 dia
A Unique Case of Granulomatosis with Polyangiitis Presenting with Proximal Muscle Weakness.
Granulomatosis with polyangiitis (GPA) is a subtype of ANCA-associated vasculitis that can have a he
Sex-stratified immune patterns across the canine lifespan and short-term responses to geroprotective interventions.
Canine models are invaluable for translational geroscience, but natural sex-associated immune aging
Pediococcus acidilactici ZQ-19 Ameliorates Ulcerative Colitis via Remodeling Gut Microbiota and Glutathione Redox Homeostasis.
Ulcerative colitis (UC) is closely linked to intestinal oxidative stress, gut dysbiosis and selenium
Short- and mid-term outcomes of SASI vs OAGB: a propensity score-matched study.
BACKGROUND: This interim analysis evaluated the safety and efficacy of single anastomosis sleeve-ile
Genetics-Informed Pharmacological Intervention in Gestational Diabetes Mellitus: Current Therapeutic Alignment, Emerging Targets and a Translational Roadmap.
BACKGROUND: Gestational diabetes mellitus (GDM) complicates roughly one in seven pregnancies and pre
Metabolic Bariatric Surgery for Cancer Prevention and Risk Reduction in Patients with Obesity: A GRADE-Based International Federation for the Surgery and Other Therapies for Obesity (IFSO) Position Statement.
BACKGROUND: Obesity is a major increasing driver of cancer burden worldwide, and intentional weight
GLP-1 receptor agonists for obstructive sleep apnea: a meta-analysis of randomized controlled trials.
PURPOSE: Weight reduction is recommended in all overweight and obese patients with obstructive sleep
Long-Term Effects of Biliopancreatic Diversion (BPD), Biliopancreatic Diversion with Duodenal Switch (BPD-DS), and Single Anastomosis Duodeno‑Ileal Bypass with Sleeve Gastrectomy (SADI‑S) in Patients with Obesity: A Meta-Analysis.
INTRODUCTION: The long-term outcomes of biliopancreatic diversion (BPD), BPD with duodenal switch (B
The neurobiology of binge eating disorder: a systematic review of studies using functional magnetic resonance imaging.
Binge eating disorder (BED) is a prevalent public health concern associated with significant medical
The lysine acetyltransferase Rv0998 coordinates transcriptional and metabolic adaptation ofto acidic pH.
(Mtb) survives host defenses by adapting to host conditions, including acid stress, during infection
'Candidatus Viridifilum namsaraevi' gen. nov., sp. nov., a new mesophilic filamentous anoxygenic phototrophic bacterium from the mesothermal lake Umkhey (Buryatia).
The evolution of phototrophy and carbon fixation in the phylum Chloroflexota remains incompletely un
Real-World Patient-Reported Outcome Comparing Antibody-Drug Conjugates and Conventional Chemotherapy in Metastatic Breast Cancer.
BACKGROUND: Antibody-drug conjugates (ADCs) have transformed second-line metastatic breast cancer (M
Gustatory dysfunction under talquetamab therapy in multiple myeloma: a cross-sectional study of patient-reported course, nutritional changes, and quality of life.
The purpose of this study is to characterize patient-reported taste disturbances, recalled symptom c
Innovative holistic treatment for CKM: what lies ahead?
Cardiovascular-kidney-metabolic (CKM) syndrome, as defined by the American Heart Association, encomp
Bidirectional Pharmacology of GIP Receptor Targeting in Obesity: Historical Foundations, Mechanistic Divergence, and Translational Boundaries.
The glucose-dependent insulinotropic polypeptide receptor (GIPR) has emerged as a central target in
Depot-specific molecular remodelling of human adipose tissue and liver following bariatric surgery revealed by longitudinal multi-omic profiling.
BACKGROUND: Obesity and its complications, including metabolic dysfunction-associated steatotic live
Hyperphagia in Prader-Willi syndrome: linking hypothalamic dysfunction to clinical assessment and management across the lifespan.
BACKGROUND: Prader-Willi syndrome (PWS) is a rare genetic neurodevelopmental disorder characterised
New insights into the pathogenesis of osteoporosis and the translational approach to personalized therapy.
Osteoporosis is increasingly recognized as a heterogeneous syndrome rather than a single disease, dr
Prevalence, risk factors and comorbidities of overweight and obesity among adults in Qatar: a cross-sectional analysis of the 2023 Stepwise Survey.
OBJECTIVES: This study examines the prevalence and risk factors associated with overweight and obesi
Sex differences in MASLD and fitness improvement during a weight loss intervention for adolescents living with obesity.
BACKGROUND AND AIMS: The interplay between liver and muscle health is incompletely understood, espec
Intestinal FXR agonism synergizes with leptin to improve obesity by reducing appetite via secretin.
Obesity is a chronic condition and is closely associated with various metabolic diseases. It has bec
Predictors of Vitamin B-12 Status in Pregnant Chilean Women During the COVID-19 Pandemic: Results of the Chilean Maternal and Infant Cohort Study-II.
BACKGROUND: Adequate vitamin B12 (B12) concentrations are essential for optimal pregnancy developmen
Oral small-molecule GLP-1RA safiglipron versus dapagliflozin in type 2 diabetes: a randomized, double-blind, active-comparator-controlled phase 3 trial.
Safiglipron is an oral small-molecule glucagon-like peptide-1 (GLP-1) receptor agonist administered
Implementation of guideline-directed cardioprotective therapy in patients living with type 2 diabetes in outpatient cardiology ambulatory setting: the Italian CardioMET registry.
BACKGROUND: To assess the implementation of guideline-directed glucose-lowering therapies with prove
Metabolic reprogramming and plasticity in breast Cancer: Mechanisms driving tumor progression, metastasis, and therapeutic resistance.
Breast cancer remains the most frequently diagnosed malignancy and a leading cause of cancer-related
The Autophagy-Epigenome Axis in Hypothalamic Neurons: A Unified Framework for Understanding Obesity Persistence and Therapeutic Resistance.
Diet-induced obesity is increasingly understood as a disorder of central regulatory failure rather t
Genes, fuel, and fate in lung cancer.
Cellular plasticity is a central feature of malignant progression, allowing tumour cells to change i
Intergenerational differences and similarities in economic well-being, family context, health, and life experiences among older adult parents and their middle-aged children: data from the Add Health and Add Health Parent Studies.
OBJECTIVES: We examined the strength of intergenerational associations between midlife adults in Add
Short-term anoxia improves postharvest quality and reduces browning-related enzyme activity in ediblemushroom.
, a nutritionally and economically valuable wild edible mushroom, is highly perishable because of it
Sex- and menopausal status-specific patterns of fat free mass loss and cardiorespiratory fitness after metabolic bariatric surgery: the Stratification of Obesity Phenotypes to Optimize Future Obesity Therapy (SOPHIA) longitudinal cohort.
BACKGROUND: Fat-free mass (FFM) loss after metabolic bariatric surgery (MBS) may influence physical
Hypothalamus Participates in Peripheral Sympathetic Hyperactivity After Acute Brain Injury by RegulatingMA Modification.
Sympathetic hyperactivity following acute brain injury (ABI) impedes recovery, yet effective treatme
Association between stigma and treatment satisfaction in patients with type 2 diabetes: a cross-sectional study.
AIMS: To investigate the comprehensive association between diabetes stigma, treatment satisfaction,
AMPK-Mediated Lipid Metabolic Reprogramming in Cancer: From Mechanisms to Targeted Therapies.
AMP-activated protein kinase (AMPK), a key regulator of cellular energy metabolism, is activated und
A Rat Model Mimicking Treatment-Induced Painful Diabetic Neuropathy Following Experimental Rapid Weight Loss.
PURPOSE: This study investigated the feasibility of constructing a painful diabetic neuropathy (PDN)
Traditional Chinese Medicine Interventions for Overweight and Obesity in Adults: An Umbrella Review and Evidence Map.
BACKGROUND: Traditional Chinese medicine (TCM) is widely used for weight management, but the reliabi
Medicaid's GLP-1 Coverage Gap: A Familiar and Correctable Policy Failure.
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