2026年10月1日（星期四）
本日收錄 40 篇文獻Levothyroxine monotherapy has limited effects on body composition in clinical and subclinical hypothyroidism: a systematic review and meta-analysis.
Clinical (CH) and subclinical (SCH) hypothyroidism reduces the metabolic rate and alter body composition. The current treatment with levothyroxine (LT4) restores the thyroid axis hormonal levels; howe
Comorbidity-specific molecular programmes of early diastolic dysfunction identify glucocorticoid receptor activation as a causal driver in obesity.
AIMS: Early diastolic dysfunction precedes the development of HFpEF, but the molecular events that initiate this process remain poorly defined. HFpEF arises in the setting of systemic comorbidities su
Semaglutide in type 2 diabetes and chronic kidney disease in Australia: practical clinical considerations from a multidisciplinary panel.
Chronic kidney disease (CKD) and cardiovascular disease (CVD) are major causes of morbidity and mortality in people with type 2 diabetes (T2D). Contemporary CKD guidelines increasingly support incorpo
Food and Health: Nutrition for Prevention and Management of Cardiovascular Disease: 2026 ACC Scientific Statement: A Report of the American College of Cardiology.
Nutrition is a foundational determinant of cardiovascular health and a central component of the prevention and management of cardiovascular disease, type 2 diabetes, obesity, chronic kidney disease, a
Adolescents' perspectives on socio-cultural influences on overweight and obesity in African countries: a systematic scoping review of qualitative studies.
INTRODUCTION: Adolescent obesity is a global public health concern, with increasing prevalence rates in many African countries. Studies have highlighted diverse social and cultural influences on weigh
Levothyroxine monotherapy has limited effects on body composition in clinical and subclinical hypothyroidism: a systematic review and meta-analysis.
Clinical (CH) and subclinical (SCH) hypothyroidism reduces the metabolic rate and alter body composi
Comorbidity-specific molecular programmes of early diastolic dysfunction identify glucocorticoid receptor activation as a causal driver in obesity.
AIMS: Early diastolic dysfunction precedes the development of HFpEF, but the molecular events that i
Semaglutide in type 2 diabetes and chronic kidney disease in Australia: practical clinical considerations from a multidisciplinary panel.
Chronic kidney disease (CKD) and cardiovascular disease (CVD) are major causes of morbidity and mort
Food and Health: Nutrition for Prevention and Management of Cardiovascular Disease: 2026 ACC Scientific Statement: A Report of the American College of Cardiology.
Nutrition is a foundational determinant of cardiovascular health and a central component of the prev
Adolescents' perspectives on socio-cultural influences on overweight and obesity in African countries: a systematic scoping review of qualitative studies.
INTRODUCTION: Adolescent obesity is a global public health concern, with increasing prevalence rates
The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Peri- and Postmenopausal Breast Cancer Outcomes.
INTRODUCTION: Studies have shown that obesity increases the risk of postmenopausal breast cancer (BC
From Awareness to Moral Redemption: Medicalisation, Stigma, and Anti-Establishment Aesthetics in the 'Obesity Without Filters' Spanish Campaign by Pharmaceutical Company Novo Nordisk.
This article examines how 'obesity' is discursively and narratively constructed in Novo Nordisk's 'O
Bridging the gap in early cardio-renal risk prevention in type 2 diabetes: evidence, guidelines, and real-world insights from the PRECARE NO LiMITS initiative.
Type 2 diabetes (T2D) is associated with a substantial burden of cardiovascular and renal complicati
TSPO deficiency uncovers a novel role for porphyrins in adipocyte lipid metabolism.
The translocator protein (TSPO) is a mitochondrial outer membrane protein enriched in lipid-metaboli
Identification and Treatment of Anorexia Nervosa in Women With Perimenopause.
Disordered eating is a common problem that midwives will encounter as frontline primary care provide
Efficacy and Safety of Dual GLP-1/Glucagon Receptor Agonism in Overweight and Obesity: A Class-Specific Systematic Review and Meta-Analysis.
BACKGROUND: Dual glucagon-like peptide-1/glucagon receptor (GLP-1/GCGR) agonists represent a novel o
Comparative Weight-Loss Outcomes Following Initiation of GLP-1 Receptor Agonists versus SGLT2 Inhibitors: A Real-World Active Comparator Study.
OBJECTIVE: To compare 12-month weight loss between GLP-1 receptor agonist (GLP-1RA) and SGLT2 inhibi
Development and Validation of Ultrasound-based Prediction Equations for Fat and Lean Mass in Adults With Obesity.
BACKGROUND & AIMS: Obesity treatment is measured by total weight loss or BMI loss, neither of which
Effect of grass crude protein concentration on rumen fermentation, blood variables, and health in recently-weaned dairy-beef calves.
Grass crude protein (CP) concentration is strongly influenced by inorganic nitrogen (N) fertiliser a
DC-CD8T cell-associated inflammation and sustained indel-derived candidate peptide exposure in radiation enteritis.
PURPOSE: Radiation enteritis (RE) is a frequent and challenging complication of radiotherapy for abd
Bariatric Surgery, Medical Weight Loss, and the Upper Aerodigestive Tract.
Obesity and intentional weight loss increasingly influence otolaryngologic disease through mechanica
Estimating the Wider Societal Impact of Semaglutide Across Multiple Indications in Canada: an Economic Evaluation.
INTRODUCTION: Medical treatments may deliver individual, healthcare and societal impact across multi
Eating Behaviors, Appetite, and Childhood Obesity in Early Childhood: A Qualitative Study of Mothers' Perceptions and Prevention Approaches.
OBJECTIVE: In early childhood, packaged food consumption, screen-based sedentary behavior, and incon
Association between physical activity, depressive symptoms, and cardiometabolic risk factors in brazilian adults.
BACKGROUND: We aimed to investigate the combined association of physical activity (PA) and the prese
Ablation of phospholipase D1 mitigates obesity-mediated pancreatic edema in a mouse model of acute pancreatitis.
Acute pancreatitis (AP) is a multifactorial inflammatory disease driven by premature activation of p
Contemporary Initial Glucose-Lowering Strategies for Type 2 Diabetes: A Systematic Review and Bayesian Network Meta-Analysis.
AIMS: To compare contemporary initial glucose-lowering strategies in adults with type 2 diabetes who
Oral small-molecule GLP-1 receptor agonist safiglipron in early type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
Safiglipron is an oral small-molecule glucagon-like peptide-1 (GLP-1) receptor agonist administered
Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.
BACKGROUND: Retatrutide is an agonist of GIP, GLP-1, and glucagon receptors, and is currently under
Metabolic reprogramming in neuromyelitis optica spectrum disorder: From astrocyte dysfunction to immune-mediated neuroinflammation.
Neuromyelitis optica spectrum disorders comprise a group of autoimmune diseases of the central nervo
The Mediterranean-style Japanese Diet: A Systematic Review of the Recommendations for an Anti-aging Lifestyle.
INTRODUCTION: The Mediterranean and the Japanese diets are followed worldwide as healthy dietary pat
Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.
Inflammatory bowel diseases (IBD) consisting of Crohn's disease (CD) and Ulcerative colitis (UC) are
Cardiometabolic and atherosclerotic cardiovascular disease outcomes associated with tirzepatide: insights from a 1-year multicenter observational study.
PURPOSE: To evaluate the association of long-term, continuous tirzepatide use with cardiometabolic r
Adherence to the Mediterranean Diet Is Associated With a Lower Risk of Obesity in Children Under 18 Years: A Comprehensive Systematic Review and Meta-Analysis.
OBJECTIVE: The Mediterranean Diet (MedDiet) is a plant-rich dietary pattern associated with favourab
Genetic Insights Into Protective Effects of GLP-1 Receptor Agonists on Stroke and Alzheimer Disease Across Ancestries.
BACKGROUND AND OBJECTIVES: Stroke and dementia are leading causes of death and disability worldwide,
EASL-EASD-EASO Guidance for the Use of Resmetirom and Semaglutide as MASH-Targeted Therapy.
Adults with metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis (MA
Severe Household Food Insecurity and Malnutrition Among School-Going Adolescents in South Punjab, Pakistan: Implications for Sustainable Development Goal 2 (A Cross-Sectional Study).
INTRODUCTION: Food insecurity and malnutrition remain major public health concerns among adolescents
Schistosomal Rectal Polyposis Mimicking Colorectal Cancer: A Case Report of a 60-mm Polyp in a Young Ethiopian Man Treated at Firoomsis General Hospital.
BACKGROUND: is a major public health problem in endemic regions, affecting over 250 million individu
Rapid community "Healthy Heart" screening to identify people at high risk of cardiovascular events.
OBJECTIVES: To evaluate the proof-of-concept feasibility of identifying individuals at high risk of
Experiencing obesity: trajectory and fruitless sacrifices to lose weight prior to bariatric surgery.
OBJECTIVE: To analyze the life trajectories of women who have lived with obesity since childhood and
Effect of FATmax-Intensity Exercise on Body Composition and Cardiovascular Health in Overweight and Obese Individuals: A Systematic Review and Meta-Analysis.
PURPOSE: To determine the effects of exercising at maximal fat oxidation (FATmax) intensity on body
Exploring the Impact of Behavioral Engagement Indicators on Pain Outcomes in AI-Enabled Musculoskeletal Rehabilitation: A Real-World Investigation.
PURPOSE: This study aimed to examine whether behavioral engagement indicators reflecting timing, rou
Household food insecurity, dietary intake, and weight status among children in Madrid, Spain: A cross-sectional study.
BACKGROUND: Household food insecurity (HFI) is increasingly prevalent and disproportionately affects
Tirzepatide among patients with psoriasis and obesity.
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GLP-1 receptor agonists versus DPP-4 inhibitors after curative resection of hepatocellular carcinoma in patients with type 2 diabetes.
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Correction: Microbiota-Gut-Brain Axis Mechanisms in Cognitive Impairment Associated with Central Obesity.
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