2026年9月22日（星期二）
本日收錄 29 篇文獻Review of the Impact of Weight Loss and Body Mass Index in Clinical Trials of Nintedanib in Interstitial Lung Disease.
INTRODUCTION: Weight loss and malnutrition are poor prognostic factors in patients with idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF). In this review, the effect of weig
Application of Machine Learning to Predict 1-Year Weight Loss Outcomes After Laparoscopic Sleeve Gastrectomy.
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is an effective treatment for obesity. This study aimed to develop and internally validate machine-learning models using routinely available preoperat
Role of Oxytocin in Obesity.
PURPOSE OF REVIEW: This review will summarize the role of the hormone, oxytocin (OT), in the control of energy balance and glucose homeostasis in pre-clinical and clinical models and the role of sex i
Quantitative Insights into Tirzepatide and Semaglutide Using Longitudinal Systems Modeling.
CONTEXT: In a 28-week clinical trial of patients with type 2 diabetes (T2D), tirzepatide 15 mg (a dual GIP/GLP-1 receptor agonist) and semaglutide 1 mg (a GLP-1 receptor agonist) both im
Association of Metabolic Score for Insulin Resistance with Intraoperative QTc Interval Changes During Laparoscopic Sleeve Gastrectomy: A Prospective Observational Study.
BACKGROUND: Preoperative metabolic status may influence cardiac repolarization under anesthesia. This study investigated the relationship between the Metabolic Score for Insulin Resistance (METS-IR) a
Review of the Impact of Weight Loss and Body Mass Index in Clinical Trials of Nintedanib in Interstitial Lung Disease.
INTRODUCTION: Weight loss and malnutrition are poor prognostic factors in patients with idiopathic p
Application of Machine Learning to Predict 1-Year Weight Loss Outcomes After Laparoscopic Sleeve Gastrectomy.
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is an effective treatment for obesity. This study
Role of Oxytocin in Obesity.
PURPOSE OF REVIEW: This review will summarize the role of the hormone, oxytocin (OT), in the control
Quantitative Insights into Tirzepatide and Semaglutide Using Longitudinal Systems Modeling.
CONTEXT: In a 28-week clinical trial of patients with type 2 diabetes (T2D), tirzepatide 15 m
Association of Metabolic Score for Insulin Resistance with Intraoperative QTc Interval Changes During Laparoscopic Sleeve Gastrectomy: A Prospective Observational Study.
BACKGROUND: Preoperative metabolic status may influence cardiac repolarization under anesthesia. Thi
Comparative effects of ketogenic diets and mediterranean diets on obesity and metabolic outcomes: a systematic review and meta-analysis.
Ketogenic diets (KD) and Mediterranean diets (MD) are among the most widely studied dietary approach
Glucomannan and resistant starch in obesity management: a systematic review of satiety, gut fermentation, and weight-related and metabolic outcomes.
Obesity is a growing global health challenge associated with dysregulated appetite, impaired gut fun
Varying In-Person Coaching: Effects on Weight and Urinary Incontinence in Women with Obesity in a 20-Week Randomized Controlled Trial.
INTRODUCTION AND HYPOTHESIS: Urinary incontinence (UI) affects 25-45% of women and is more common in
Dissection of Obesity-Induced Spermatogenic Dysfunction at Single-Cell Resolution.
BACKGROUND: Obesity is a major risk factor for male infertility; however, how different obesity etio
Periodontitis Is Associated With Higher Blood Pressure and Pulse Wave Velocity in Late Adolescence: A Population-Based Study.
OBJECTIVE: We hypothesized that periodontal tissue disruption and vascular dysfunction may coexist i
Type 1 diabetes and cardiovascular medicine.
There are an estimated 9.5 million people living with type 1 diabetes (T1D) globally, with cardiovas
Hemoglobin Aand Weight Changes Associated With Grocery Delivery and Low-Carbohydrate Education in Adults With Type 2 Diabetes and Food Insecurity: Observational Quality Improvement Cohort Study.
BACKGROUND: Type 2 diabetes mellitus (T2D) is one of the most significant chronic health challenges
Modulation of circulating osteocalcin-expressing monocytes by glucagon like peptide-1 receptor agonists in type 2 diabetes: an exploratory pilot study.
CONTEXT: The phenotypic drift of circulating monocytes toward osteoblast-like cells expressing osteo
Therapy resistance-related ncRNAs in cervical cancer: biomarkers and therapeutic targets.
BACKGROUND: Cervical cancer remains a major cause of cancer-related morbidity and mortality, and res
Effects of Empagliflozin on Cardiovascular Outcomes Are Consistent Across Sociodemographic Subgroups: A Real-World Analysis From the EMPRISE Study.
OBJECTIVE: We aimed to explore the heterogeneity of empagliflozin treatment effects on major adverse
Heart failure with a preserved ejection fraction: synergy between cardiac and extracardiac mechanisms and effects of novel therapies.
Heart failure with preserved ejection fraction (HFpEF) is a systemic disease in which metabolic como
Agreement of Over-the-Counter Continuous Glucose Monitors With Capillary-Meter Glucose in Young Adults Without Diabetes.
BACKGROUND: Over-the-counter continuous glucose monitors (OTC CGMs) are increasingly used by individ
Preclinical and First-In-Human Evaluation of Ribupatide (HRS9531), a Dual GLP-1/GIP Receptor Agonist.
AIMS: This study assessed the preclinical and clinical pharmacokinetics (PK), pharmacodynamics (PD),
Effect of Semaglutide on Thigh Skeletal Muscle Volume, Fat Infiltration and Physical Function in People With Obesity: Secondary Analysis of STEP UP.
AIMS: To assess the effect of semaglutide on body composition and physical function. MATERIALS AND M
Economic evaluations of antiobesity medications: A systematic literature review.
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved an
Cargo-aware design of dissolving microneedles: an FEA-guided rational framework reveals distinct delivery mechanisms for small and large molecules.
Transdermal delivery of glucagon-like peptide-1 receptor agonists (GLP-1RAs) such as semaglutide (SE
Patterns of Ultra-Processed Food Consumption and Their Associations With Body Composition in Primary School Children in Semarang City, Indonesia.
AIMS: This study aimed to examine the association between ultra-processed food (UPF) consumption and
Sex and Socioeconomic Differences in the Initiation of SGLT2 Inhibitors and GLP-1 Receptor Agonists in Patients With Type 2 Diabetes and Cardiovascular Disease: A Nationwide Cohort Study.
AIMS: Cardioprotective glucose-lowering drugs (GLDs) remain underutilised in individuals with Type 2
Association of tirzepatide versus Glucagon-Like Peptide-1 receptor agonists with oral and periodontal outcomes in patients with type 2 Diabetes: A Global propensity Score-Matched cohort study.
AIMS: To evaluate the association between tirzepatide and recorded oral and periodontal outcomes com
mTOR signaling in aging: from causality to geroprotective interventions and hallmark-level outcomes.
The mechanistic target of rapamycin (mTOR) pathway is an important integrator of processes involved
Applicability of Non-Invasive Eligibility Criteria for MASH Pharmacotherapy: A Multicentre Cohort Study.
BACKGROUND AND AIMS: Non-invasive tests (NITs) are increasingly used to guide patient selection for
Semaglutide Effects on Insulin Sensitivity and β-Cell Function in Patients With Schizophrenia, Prediabetes, and Obesity Treated With Second-Generation Antipsychotics: Findings From the HISTORI Trial, a 30-Week Randomized, Placebo-Controlled Trial With Semaglutide 1.0 mg Weekly. Diabetes Care 2026;49:XXXX-XXXX.
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Response to Comment on Meier et al. Different Metabolic Responses to Long-term Weight Loss After Lifestyle Intervention Among Type 2 Diabetes Risk Clusters: Results From the TULIP Study.
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Comment on Meier et al. Different Metabolic Responses to Long-term Weight Loss After Lifestyle Intervention Among Type 2 Diabetes Risk Clusters: Results From the TULIP Study.
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