2026年6月24日（星期三）
本日收錄 30 篇文獻Experience with Tirzepatide and Weight Management During and After a Clinical Trial in Japanese Patients with Obesity Disease: A Qualitative Study.
INTRODUCTION: The phase 3 SURMOUNT-J clinical trial showed that Japanese adults with obesity disease achieved clinically meaningful body weight loss with once-weekly tirzepatide for 72 weeks
Treating Severe Obesity: A Medical Perspective.
The global prevalence of obesity has increased substantially over the past several decades, with the most rapid growth occurring among individuals at the highest levels of body mass index (BMI). Great
Adjunctive use of glucagon-like peptide-1 receptor agonists after bariatric surgery: updated systematic review and meta-analysis of randomized controlled trials.
AIMS: We meta-analyzed randomized trials to assess efficacy and safety of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) after bariatric surgery. METHODS: We searched PubMed, Embase, and Cochra
Long-term course and predictors of postpartum urinary incontinence: a three-year cohort in Portuguese women.
PURPOSE: Urinary incontinence (UI) is a frequent yet often underrecognized morbidity among postpartum women. Understanding its prevalence, trajectory, and risk factors is essential for informing preve
Semaglutide for Primary Prevention of Major Adverse Cardiac and Cerebrovascular Events in Patients with Type 2 Diabetes and Comorbid Rheumatoid Arthritis: A Target-Trial Emulation.
BACKGROUND: Rheumatoid arthritis (RA)-related physical limitations often hinder sustained physical activity and weight management, thereby amplifying cardiovascular risk through adverse metabolic prof
Experience with Tirzepatide and Weight Management During and After a Clinical Trial in Japanese Patients with Obesity Disease: A Qualitative Study.
INTRODUCTION: The phase 3 SURMOUNT-J clinical trial showed that Japanese adults with obesity di
Treating Severe Obesity: A Medical Perspective.
The global prevalence of obesity has increased substantially over the past several decades, with the
Adjunctive use of glucagon-like peptide-1 receptor agonists after bariatric surgery: updated systematic review and meta-analysis of randomized controlled trials.
AIMS: We meta-analyzed randomized trials to assess efficacy and safety of glucagon-like peptide-1 re
Long-term course and predictors of postpartum urinary incontinence: a three-year cohort in Portuguese women.
PURPOSE: Urinary incontinence (UI) is a frequent yet often underrecognized morbidity among postpartu
Semaglutide for Primary Prevention of Major Adverse Cardiac and Cerebrovascular Events in Patients with Type 2 Diabetes and Comorbid Rheumatoid Arthritis: A Target-Trial Emulation.
BACKGROUND: Rheumatoid arthritis (RA)-related physical limitations often hinder sustained physical a
Erratum.
In the Abstract entitled "GLP-1 Receptor Agonist Use in Children and Young People with Severe and Co
Mechanotherapeutic biomaterials: Overcoming physical barriers to enhance intratumoral drug delivery in solid tumours.
The clinical translation of nanomedicine for solid tumours remains limited despite substantial advan
Pregabalin enhances the proliferative potential of pancreatic cancer in vitro but not in mice with pancreatic cancer.
BACKGROUND: We previously reported that mirogabalin, a selective voltage-gated calcium channel ;
The effects of exercise interventions on weight regain after weight loss: a systematic review and meta-analysis.
To systematically evaluate the effects of exercise during the post-weight-loss maintenance phase on
Dietary yacon concentrate reshapes microbial-metabolite crosstalk to inhibit colorectal cancer.
Yacon concentrate, which is rich in fructan, phenolic compounds, and flavonoids, exhibits notable nu
HRS-7535, an oral small-molecule GLP-1 receptor agonist, in Chinese adults with obesity without diabetes: a randomized, double-blind, placebo-controlled phase 2 trial.
HRS-7535 is an orally active small-molecule glucagon-like peptide-1 receptor agonist that showed wei
Dual Glucagon and GLP-1 Receptor Agonist Survodutide Improves Biomarkers of Beta-Cell Function and Insulin Sensitivity in People With Type 2 Diabetes or Living With Overweight/Obesity.
AIMS: This post hoc analysis evaluated the effect of survodutide on beta-cell function, insulin sens
Effects of Weight-Loss Interventions on Kidney, Cardiometabolic and Anthropometric Outcomes in Adults With CKD and Overweight or Obesity: A Systematic Review and Meta-Analysis.
BACKGROUND AND AIMS: Obesity and chronic kidney disease (CKD) are highly prevalent conditions with s
The case to augment healthcare professional training for the treatment of obesity by integrating cognitive dissonance interventions to reduce weight stigma.
Obesity is associated with risk for chronic health problems and increased mortality. Weight stigma,
Impact of weight loss and reduction of ultra-processed foods on liver fat content in MASLD: a randomized controlled trial.
BACKGROUND & AIMS: Dietary interventions are a cornerstone of management for metabolic dysfunction-a
GLP-1 Receptor Agonist Therapy in Cystic Fibrosis-Related Diabetes: Insights from a Pilot Implementation Program.
Cystic fibrosis-related diabetes (CFRD) management is evolving as the CF population experiences incr
Laparoscopic Hiatus Hernia Repair with BIO-Amesh is Safe and Effective for Patients Suffering Severe Gastro-Esophageal Reflux Disease After Sleeve Gastrectomy - A Single Surgeon Experience.
INTRODUCTION: There is a complex relationship between gastroesophageal reflux disease (GORD), hiatus
Efficacy and Safety of Bariatric Surgery in Acquired Hypothalamic Obesity: A Systematic Review and Individual Patient Data Meta-Analysis.
OBJECTIVE: This work aimed to investigate the efficacy and safety of Roux-en-Y gastric bypass (RYGB)
Gestational diabetes mellitus and maternal-infant microbiome axis: mechanistic insights and therapeutic interventions.
BACKGROUND: Gestational diabetes mellitus (GDM) alters maternal metabolism and the gut microbiota, t
Macronutrient mixtures and interactions in health and disease.
Nutrition shapes development, health and risk of disease over the life course and across generations
"The Accelerating Burden of Colorectal Cancer Mortality With Co-Documented Metabolic Comorbidity in the United States: A 26-Year Analysis of Trends, Disparities, and Projections to 2031".
BACKGROUND: Colorectal cancer (CRC), the second leading cause of cancer-related death worldwide, has
Metabolic rewiring at the pyruvate node contributes to severe pneumonia and attenuation of T cell responses in serotype 3 Streptococcus pneumoniae infection.
BACKGROUND: Serotype 3 (ST3) Streptococcus pneumoniae remains a major cause of invasive pneumococcal
Takeda G-protein-coupled receptor 5 and farnesoid X receptor agonists for diabetes treatment: a patent review and clinical advancements (2015-present).
INTRODUCTION: Takeda G-protein-coupled receptor 5 (TGR5) and farnesoid X receptor (FXR) are bile aci
Glucagon-Like Peptide-1 Receptor Agonists and Incident Major Adverse Liver Outcomes in People With Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease.
AIMS: Treatment options for metabolic dysfunction-associated steatotic liver disease (MASLD) are lim
A rare case of syphilitic hepatic inflammatory pseudotumor misdiagnosed as liver metastasis: Case report and mini-review.
RATIONALE: Syphilitic hepatic inflammatory pseudotumor is an exceedingly rare benign hepatic manifes
Elevated platelet-to-lymphocyte ratio is associated with increased breast cancer risk: A cross-sectional analysis of the NHANES 2009 to 2020.
Inflammation is a recognized driver of tumorigenesis, particularly in breast cancer. The platelet-to
A scoping review of patient-provider communication about weight and weight management among adults with higher body weight.
OBJECTIVES: This scoping review describes the characteristics of studies that were designed to addre
Nicotinamide enhances lipid deposition and thermogenesis in goat brown adipocytes.
Brown adipose tissue (BAT) serves as a crucial thermogenic tissue in newborn goats, playing an impor
Maternal hypothalamic response to LPS is inhibited by pregnancy and remains unchanged in multiparity-associated obesity.
Multiparity increases the risk of obesity in both humans and animal models. We have previously disco
Beyond the Scale: Patient Perceptions and Experiences of Bariatric Surgery Support-A Qualitative Analysis of the BELONG II Study.
To examine surgical experiences of diverse participants with obesity who underwent bariatric surgery