今日文獻聚焦於針灸與中草藥在精神疾病中的機制研究,特別是經絡調節、腸腦軸與神經可塑性方面的進展顯著,臨床轉化潛力高,顯示中醫精神醫學正從經驗應用向機制闡釋與多靶點協同調節方向深化。
Zhen ci yan jiu = Acupuncture research · Electroacupuncture improves synaptic plasticity mediated by Glu/GABA balance in the medial prefrontal cortex of mice with perimenopausal depression
電針經調節前额叶皮层Glu/GABA平衡,改善围绝经期抑郁样行為及突触結構與功能可塑性,為更年期抑鬱症的非藥物治療提供機制依據。
Neuropsychiatric disease and treatment · Does the Microbiota-Gut-Brain Axis Mediate the Antidepressant Effects of Acupuncture? A Structured Review of Preclinical and Clinical Evidence.
系統性回顧證實針灸可透過調節腸道菌群與代謝物質(如SCFAs)影響中樞神經功能,從而發揮抗抑鬱效果,腸腦軸為其重要介導路徑。
Chinese medicine · Modified Gan-Mai-Da-Zao decoction for behavioral and psychological symptoms of dementia: preclinical efficacy and molecular mechanisms.
修復甘麥大棗湯在動物模型中展現顯著的鎮靜催眠、抗焦慮與抗抑郁樣活性,潛力可用於改善癡呆行為與心理症狀(BPSD)。
Zhen ci yan jiu = Acupuncture research · [Research progress on neural circuit mechanisms of acupuncture intervention in pain-related emotions].
針灸可調節多個與焦慮、抑鬱及疼痛厭惡記憶相關的關鍵神經迴路(如rACC→thalamus、mPFC→amygdala),從而緩解疼痛伴隨的負面情緒。
International immunopharmacology · Traditional Chinese medicine for neutrophil-mediated acute lung injury: from single-mechanism targeting to multi-mechanism synergistic regulation.
中醫藥透過調節中性粒細胞的募集、激活、遷移及凋亡等多個環節,發揮多靶點協同作用,對急性肺損傷/急性呼吸窘迫症候群具潛在治療價值。
Geriatric nursing (New York, N.Y.)
系統性回顧與統合分析顯示自我按壓穴位可顯著改善骨關節炎患者的疼痛、功能、睡眠及生活品質,為非藥物自我管理提供有效護理策略。