今日文獻重點關注「共病機制」與「共病治療」,特別是中醫在處理身心症候群(如失眠-抑鬱、RA伴隨情緒問題)的價值日益受到重視,並揭示了柴胡龍骨牡蠣湯與新代謝標靶(6PGD)在抑鬱症治療中的潛力。
Zhen ci yan jiu = Acupuncture research · [From clinical benefit to mechanism analysis: research progress on the combined intervention of intelligence three-needling and other therapies in vascular dementia]
系統性回顧指出「智針」(神庭、本神穴)結合針灸、藥物或復健,能顯著改善血管性失智症患者的認知功能,並提供了初步的臨床機制支持。
Journal of ethnopharmacology · Neuroprotective effects of Chaihu-Longgu-Muli Decoction in an insomnia-depression comorbidity model via Galectin-3-dependent JAK2/STAT3 inhibition
研究證實經典方劑柴胡龍骨牡蠣湯透過抑制Galectin-3/JAK2/STAT3信號傳遞路徑,有效緩解失眠與抑鬱的共病症狀,具有神經保護作用。
Journal of ethnopharmacology · San Wei Tan Xiang (SWTX) ameliorates depressive-like behaviors by modulating 6-phosphogluconate dehydrogenase (6PGD) activity in mice.
研究發現藏族經典藥方三味檀香能調節關鍵代謝酶6PGD,進而緩解皮質醇誘導的小鼠抑鬱行為,開啟了代謝視角治療抑鬱的新途徑。
Zhen ci yan jiu = Acupuncture research · [Clinical study on efficacy and mechanism of separated moxibustion in the treatment of rheumatoid arthritis and related negative emotions based on gut microbiota]
臨床試驗顯示,在常規藥物基礎上加做分離式艾灸(足三里、腎俞等)不僅能緩解關節症狀,還能顯著改善患者的負面情緒,且機制與腸道菌群調節有關。
Neuropsychiatric disease and treatment · Auricular Acupressure for Depressive and Anxiety Symptoms in Women with Premenstrual Dysphoric Disorder: Protocol for a Pilot Randomized Sham-Controlled Trial.
此計畫書旨在評估耳穴壓針對改善PMDD女性焦慮抑鬱症狀的可行性、依從性及初步安全性,為未來大規模研究奠定基礎。
Complementary therapies in medicine
對先前發表於《Complementary Therapies in Medicine》關於臉頰針治療抑鬱症研究的勘誤說明。
Journal of Zhejiang University. Medical sciences
系統性回顧探討了睡眠障礙與IVF/ET成功的關聯性,指出良好的睡眠品質可顯著提高臨床妊娠率。