今日文獻聚焦於睡眠障礙的神經生理機制與臨床共病,尤其強調腦膠淋巴系統在不寧腿症中的角色、睡眠呼吸中止症對心腦血管的影響,以及社會壓力對睡眠品質的顯著影響,顯示跨領域整合趨勢明顯。
Sleep medicine · Alterations in glymphatic system-related MRI markers in patients with primary restless legs syndrome and association with disease severity.
發現不寧腿症患者腦膠淋巴功能受損(DTI-ALPS下降、自由水增加),且自由水與臨床評分顯著正相關,首次以影像證明其神經生理病機。
Sleep medicine · Prevalence and associated factors of sleep quality in a middle eastern country undergoing an economic - Political unrest and war conflicts.
在經歷危機的黎巴嫩民眾中,超過六成睡眠品質不良,且焦慮、憂鬱、糖尿病與睡眠呼吸中止症為獨立危險因子,凸顯社會結構對睡眠健康的衝擊。
Sleep · Brain MRI Changes Following Continuous Positive Airway Pressure Therapy in Adults with Obstructive Sleep Apnea: A Systematic Review.
雖有零星報告指出CPAP治療後腦部結構與功能可部分改善,但因研究設計不一、樣本小及方法異質,無法證實具重複性的腦部恢復效應。
Nature and science of sleep · Effect of Hypertension on Left Ventricular Diastolic Dysfunction Associated with Obstructive Sleep Apnea.
高血壓與 OSA 獨立且互為乘法式影響左心室舒張功能(E/e'升高),共存時傷害最嚴重,提示雙重風險需積極干預。
Sleep medicine · Sleep-disordered breathing during pregnancy and the risk of postpartum depression.
懷孕中期AHI為產後憂鬱獨立危險因子(OR=1.024),而較高MinSpO2具有保護作用;孕早期則無顯著關聯,提示時間窗口的重要性。