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Sex Brain · 性學文獻日報

📅 2026年7月8日 📊 47 篇文獻 Powered by PubMed + Zhipu AI

📋 今日文獻趨勢

今日文獻涵蓋精準醫療、藥物警戒與性諮商三大亮點，PDE5A藥物基因學研究為勃起功能障礙的個體化治療開啟新頁，Flibanserin十年真實世界安全性數據則為女性性慾低落治療提供重要用藥參考。

⭐今日精選 TOP Picks

#1 💊 高實用性

Flibanserin真實世界使用安全性：美國FDA不良事件通報系統十年藥物警戒證據

Sexual Health · Flibanserin safety in real-world use: a decade of US Food and Drug Administration Adverse Event Reporting System pharmacovigilance evidence.

透過分析FDA不良事件通報系統2016至2025年資料，首次系統性揭示Flibanserin在真實世界中的安全性輪廓，為臨床處方提供關鍵藥物警戒參考。

P使用Flibanserin的患者（源自FAERS資料庫）

IFlibanserin（作為主要懷疑藥物）

CFAERS資料庫中其他藥物通報比例

O不良事件發生率、不成比例分析（PRR、ROR）結果及標準化MedDRA編碼之安全訊號

女性性功能障礙性慾低落身心醫學閱讀原文 →

#2 🧬 高實用性

PDE5A基因變異與糖尿病合併勃起功能障礙男性對他達拉反應之關聯：前瞻性概念驗證藥物基因學研究

The Journal of Sexual Medicine · PDE5A variation is associated with tadalafil response in men with diabetes mellitus and erectile dysfunction: a prospective proof-of-concept pharmacogenetic study.

首次前瞻性證實PDE5A基因變異可預測糖尿病合併勃起功能障礙患者對他達拉非的治療反應，為PDE5抑制劑的精準醫療奠定基礎。

P合併勃起功能障礙之糖尿病男性患者

IPDE5A基因分型

C不同PDE5A基因變異型別之間

O他達拉非治療反應差異（臨床療效指標）

勃起功能障礙性神經科學身心醫學閱讀原文 →

#3 ⚠️ 高實用性

陰莖增大術前應篩檢身體畸形恐懼症之論證

The Journal of Sexual Medicine · An argument to screen for body dysmorphic disorder prior to penile augmentation procedures.

強烈主張於陰莖增大術前常規篩檢身體畸形恐懼症，以避免對此類高風險族群進行不必要且可能加重症狀的手術介入。

P尋求陰莖增大術之男性

I術前身體畸形恐懼症（BDD）篩檢

C未進行BDD篩檢之常規術前評估

O術後滿意度、BDD症狀惡化風險、重複手術需求

性健康身心醫學性功能障礙閱讀原文 →

#4 💑 高實用性

成人伴侶中完美主義、情感親密與關係及性滿意度之縱向伴侶關聯研究

Journal of Sex & Marital Therapy · Longitudinal Dyadic Associations Between Perfectionism, Emotional Intimacy, and Relationship and Sexual Satisfaction in Adult Couples.

透過縱向伴侶資料揭示多維度完美主義透過損害情感親密進而降低關係與性滿意度的機制，為伴侶治療提供明確介入焦點。

P成人伴侶

I多維度完美主義（自我取向、他人取向、社會規定期望）

C不同完美主義維度及伴侶間交叉影響

O情感親密程度、關係滿意度、性滿意度之縱向變化

性諮商伴侶治療性滿意度閱讀原文 →

#5 💪 中實用性

精神疾病患者性賦權之相關因素：橫斷面研究

Journal of Sex & Marital Therapy · Factors Associated with Sexual Empowerment in People with Mental Illness: A Cross-Sectional Study.

確認性病知識、自尊、性自我污名、溝通技巧及是否能接觸性健康諮詢資源等七大因素與精神疾病患者性賦權顯著相關，點出此弱势族群性健康促進的具體切入點。

P300名成年精神疾病患者

I性傳染病與避孕知識、孕前照護知識、自尊、性自我污名、伴侶需求、溝通技巧、性健康諮詢資源可近性

C高 vs. 低性賦權組別之變項差異

O性賦權程度（性關係中的自我決定能力）

性健康性諮商身心醫學閱讀原文 →

#6 🌍 中實用性

全球恐同因素預測之機器學習研究

Archives of Sexual Behavior · A Machine Learning Study of Predictors of Homophobia Across the Globe.

運用隨機森林演算法分析62國資料，識別出傳統道德規範、宗教信仰、威權主義、外群不信任等八大集群共78個恐同態度頂級預測因子。

P世界價值觀調查中62國之受訪者

I超過350個潛在預測變項（涵蓋社會、宗教、政治、心理等面向）

C隨機森林模型中各變項之預測重要性排名

O恐同態度（標準化測量指標）

LGBTQ+性少數健康公共衛生閱讀原文 →

#7 🩻 中實用性

評估MRI於完全雄激素不敏感症候群陰道測量之準確度：先導研究

The Journal of Sexual Medicine · Assessing the accuracy of MRI for vaginal measurements in complete androgen insensitivity syndrome: a pilot study.

先導性驗證MRI作為完全雄激素不敏感症候群患者陰道長度與形態測量工具的準確度，提供非侵入性評估的新選擇。

P完全雄激素不敏感症候群（CAIS）患者

IMRI影像陰道測量

C臨床標準陰道測量方法（如體檢或超音波）

OMRI測量值與標準方法之一致性、準確度指標

跨性別健康性健康身心醫學閱讀原文 →

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💞 中

Longitudinal Dyadic Associations Between Perfectionism, Emotional Intimacy, and Relationship and Sexual Satisfaction in Adult Couples.

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Perfectionism is a personality trait marked by excessive standards of performance and a tendency to critically evalua...

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💞 中

Factors Associated with Sexual Empowerment in People with Mental Illness: A Cross-Sectional Study.

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🌍 中

A Machine Learning Study of Predictors of Homophobia Across the Globe.

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🧠 中

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📄 中

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🩺 中

PDE5A variation is associated with tadalafil response in men with diabetes mellitus and erectile dysfunction: a prospective proof-of-concept pharmacogenetic study.

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📄 低

Assessing the accuracy of MRI for vaginal measurements in complete androgen insensitivity syndrome: a pilot study.

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📄 低

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💞 低

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💭 低

Flibanserin safety in real-world use: a decade of US Food and Drug Administration Adverse Event Reporting System pharmacovigilance evidence.

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🧠 低

Salivary oxytocin research clings strongly to early theories, despite new frameworks attributing versatile roles to the neuropeptide.

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🩺 低

Regional differences in corpora cavernosa morphology exist along the proximal to distal axis of the penis in adult Sprague Dawley rats.

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🌍 低

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📄 低

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💞 低

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🩺 低

Bakh formula ameliorates high-fat diet-induced erectile dysfunction in rats via coordinated restoration of metabolic and tissue homeostasis.

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🏳️‍🌈 低

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🩺 低

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[This corrects the article DOI: 10.1093/sexmed/qfaf101.].

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🌍 低

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🫧 低

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💞 低

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💞 低

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🌍 低

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📊主題分佈

性功能障礙

女性性功能障礙

勃起功能障礙

性諮商

伴侶治療

性滿意度

性健康

身心醫學

LGBTQ+

性少數健康

跨性別健康

公共衛生

性神經科學

🏷️關鍵字

Flibanserin安全性PDE5A藥物基因學身體畸形恐懼症篩檢完美主義與性滿意度精神疾病性賦權恐同預測因子CAIS影像評估