Psychedelic Brain · 迷幻研究文獻日報 · 2026年7月27日（週一）

⭐今日精選 TOP Picks

#1 🔬 中實用性

Development and clinical evaluation of a nanoemulsion for buccal delivery of cannabis extract in refractory chronic pain.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · Development and clinical evaluation of a nanoemulsion for buccal delivery of cannabis extract in refractory chronic pain.

Cannabinoid-based therapies have gained increasing attention for the management of chronic and treatment-resistant pain, although their clinical application is limited by the poor aqueous solubility a

Buccal deliveryCannabis sativa extractNanoemulsion 閱讀原文 →

#2 🔬 中實用性

Implementation factors shaping British Columbia's drug decriminalization pilot: A systematic review with narrative synthesis.

The International journal on drug policy · Implementation factors shaping British Columbia's drug decriminalization pilot: A systematic review with narrative synthesis.

BACKGROUND: In January 2023, British Columbia (BC) became the first Canadian province to implement a legally sanctioned drug decriminalization policy, removing criminal penalties for adults possessing

CanadaDrug decriminalizationDrug policy 閱讀原文 →

#3 🔬 中實用性

MDMA as an early post-trauma intervention in a translational animal model of PTSD.

Progress in neuro-psychopharmacology & biological psychiatry · MDMA as an early post-trauma intervention in a translational animal model of PTSD.

Post-traumatic stress disorder (PTSD) remains difficult to prevent after trauma, highlighting the need for early interventions that reduce the risk of chronic symptom development. This controlled stud

Animal modelEarly interventionGlucocorticoids 閱讀原文 →

#4 🔬 中實用性

Substance use and mental health outcomes among gay and bisexual men in South Korea: a cross-sectional study.

Addictive behaviors reports · Substance use and mental health outcomes among gay and bisexual men in South Korea: a cross-sectional study.

PURPOSE: This study investigated the prevalence of substance use among gay and bisexual men in South Korea and examined its association with mental health outcomes. METHODS: Data were drawn from a nat

Gay and bisexual menMental healthSexual minority men 閱讀原文 →

#5 🔬 中實用性

Time-dependent effects of rapid-acting antidepressants in iPSC-derived neurons from treatment-resistant depression and healthy volunteers.

Molecular psychiatry · Time-dependent effects of rapid-acting antidepressants in iPSC-derived neurons from treatment-resistant depression and healthy volunteers.

Rapid-acting antidepressants like ketamine and serotonergic psychedelics show promise for treatment-resistant depression (TRD), but the molecular mechanisms that contribute to their therapeutic effect

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📚其他值得關注的文獻

📄 中

Contribution of the Serotonin 5-HT

Neuropsychopharmacology reports

Psychedelics such as psilocybin and lysergic acid diethylamide (LSD) exert hallucinogenic effects through stimulation of serotonin 5-HT2A receptors (5

psilocinserotonin 5‐HT2A receptor PubMed →

📄 中

Prescribing bias and adverse outcomes of esketamine in major depression comorbid substance.

Journal of affective disorders

OBJECTIVE: Little is known about esketamine's effectiveness for patients with major depressive disorder (MDD) comorbid substance use disorders (SUD).

EsketamineMajor depressive disorder PubMed →