今日文獻聚焦於精準營養評估工具的臨床應用,特別是CT身體組成分析結合GLIM標準對癌症患者預後的預測價值,以及低GI飲食介入對MASLD肝脂減少的初探性證據。
Journal of the Academy of Nutrition and Dietetics · Incorporating CT-Derived Body Composition analysis into the Global Leadership Initiative on Malnutrition criteria is associated with overall survival: findings from an international cancer cohort.
於1,118名癌症患者中證實,將CT肌肉量評估納入GLIM標準可偵測到42.2%的低肌肉量個案,遠高於傳統體重減輕指標的24.8%,且能更精準預測不同治療意圖患者的總生存期。
Clinical nutrition ESPEN · The effect of a two-week low glycaemic index, higher fibre diet versus high glycaemic index diet on body composition, ectopic lipids, inflammatory biomarkers, gastrointestinal hormones and gut microbiota in Metabolic dysfunction-associated Steatotic Liver Disease (MASLD): A pilot randomized cross-over study.
在等熱量與等巨量營養素條件下,僅兩週的低GI飲食即顯著降低MASLD患者肝臟脂肪比例達8.57%,並改善HOMA-IR、體重及發炎指標IL-6。
Journal of the Academy of Nutrition and Dietetics · Application of the Total Nutrient Index as a Precision Nutrition Tool to Address Dietary Recommendations Across the Life Course.
基於NHANES近2萬名受訪者資料,開發涵蓋食物與膳食補充劑的總營養指數(TNI),發現美國人平均得分72分,且各年齡層差異顯著,幼兒與老年者表現較佳。
Clinical nutrition ESPEN · Molecular Pathways and Therapeutic Frontiers in Cancer Cachexia: Integrating Inflammatory and Non-Inflammatory Mechanisms.
系統性回顧癌症惡病質的發炎(IL-6、TNF-α)與非發炎(PIF、LMF、肌抑素)雙軸機制,強調結合細胞因子抑制劑、鐵死亡阻斷劑與營養運動之多模式策略為未來方向。