Highly Sensitive · 高敏感研究文獻日報

📅 2026年8月26日 📊 28 篇文獻 Powered by PubMed + NVIDIA Nemotron

📋 今日文獻趨勢

大部分新文獻聚焦於疾病模型與代謝調節,較少直接探討高敏感特質(SPS)與環境敏感度的關聯,顯示高敏感研究仍在新興。

⭐今日精選 TOP Picks
📚其他值得關注的文獻
🧬 低

Ferroptotic stress promotes hematopoietic stem cell aging through S1P-dependent epigenetic and lipid remodeling.

Blood

識別S1P-HDAC-Lpcat2通路在HSC老化中的角色,為代謝目標提供新思路。

🩸 中

Maternal and Neonatal Factors Impacting the Volume and Cellular Composition of Umbilical Cord Blood.

Stem cell reviews and reports

母體BMI、胎兒長度與血液pO2與UCB細胞量相關,提供採集策略參考。

🐖 低

Using High-Dimensional Environmental Covariates to Study Genotype by Environment Interaction for Reproductive Traits in Duroc Boars.

Journal of animal science

整合環境协變量探討基因-環境互動,發現特定氣象因素與精子品質相關。

💉 中

GAA engineered to improve cellular uptake enhances correction in a preclinical hematopoietic stem cell gene therapy model of Pompe disease.

Molecular therapy. Advances

設計IGF2受容體標靶GAA,提升細胞內傳遞效率,具臨床潛力。

⚗️ 高

Benzene Metabolite-Targeted Gene ATF7IP2 Drives Glutamate Metabolic Reprogramming to Promote Acute Myeloid Leukemia Initiation.

Toxicology letters

發現ATF7IP2調節谷氨酸代謝,促進急性髓系白血病前體細胞形成,提供治療新靶點。

🧪 低

Sex-specific responses to repeated dose of abamectin in albino rats: a focus on cytotoxicity, genotoxicity, and pro-inflammatory signaling.

Naunyn-Schmiedeberg's archives of pharmacology

女性對阿拜美ectin更敏感,顯示性別差異在毒理評估中重要。

🧬 中

Geneformer-guided multiomics integration identifies Pbx1 as a network hub of hematopoietic stem cell aging.

Science advances

利用Geneformer發現Pbx1調控老化HSC的轉錄程式,為再生醫學提供新靶點。

🫁 高

Intrahepatic Platelets Orchestrate Microenvironmental Remodelling and Cellular Crosstalk in Liver Fibrosis.

Liver international : official journal of the International Association for the Study of the Liver

肝內血小板在纖維化微環境中扮演關鍵角色,提供新的治療視角。

🔬 中

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review).

International journal of molecular medicine

系統性總結纖維化各器官的轉錄網路,強調HSC激活的關鍵因子。

🌿 高

Berberine from Traditional Chinese Medicine in Liver Diseases: From Steatosis to Fibrosis and Hepatic Malignancies.

The American journal of Chinese medicine

Berberine通過多條通路抑制肝 stellate cell 活化,具抗纖維化潛力。

🤖 中

Hematopoietic stem cell aging: a review of transcriptional and multi-omics insights and potential paths for AI integration.

Experimental & molecular medicine

整合單細胞與多組學資料,探討AI在HSC老化預測中的應用前景。

😊 低

The impact of sensory processing sensitivity on subtle dynamic facial expression recognition and metacognitive awareness.

Psychological research

高SPS提升對細微表情的辨識與自我監控,顯示感官敏感的認知優勢。

🦯 低

Understanding AI-powered assistive technologies for visual impairment: a review of functional features.

Disability and rehabilitation. Assistive technology

彙總AI輔助科技在視覺障礙領域的功能與限制,提供設計建議。

💊 高

Liver fibrosis: Pathogenesis and innovative nanoparticle-based therapeutic strategies.

International journal of pharmaceutics: X

概述肝纖維化機制與奈米藥物遞送的最新進展,聚焦精準治療。

🧪 低

Oleic acid modulates perilipin expression and lipid droplet contents in TGFβ1 activated HSCs.

Biochemical and biophysical research communications

脂肪酸處理影響Perilipin表現,暗示代謝重塑在纖維化中的角色。

💥 高

Pterostilbene alleviates liver fibrosis by triggering ferroptosis in activated hepatic stellate cells through regulation of PI3K/Akt signaling pathway.

International immunopharmacology

Pterostilbene透過PI3K/Akt誘導Ferroptosis,減少HSC活化,具治療潛力。

⚗️ 中

G22037, a novel oxadiazole-pyrazole derivative, attenuates liver fibrosis by targeting annexin A5 and inhibition of ER stress-dependent hepatic stellate cell activation.

Biochemical pharmacology

新化合物G22037抑制ANXA5與ER壓力,減緩HSC活化,展現雙重作用。

🔬 中

Discovery of Arenarine D and its active derivatives as a novel lead targeting DYRK1B/MYH9 in hepatic fibrosis.

European journal of medicinal chemistry

天然甙類衍生物作為DYRK1B/MYH9雙重靶點,抑制肝纖維化進程。

👶 高

The relationship between home environment and infant neuropsychological outcomes: Comparison between preterm and full-term infants.

Early human development

低品質居家環境對預成熟兒社交行為影響尤大,支持差異易感性模型。

🧬 中

HSP10, HSP60, and HSP70 overexpression associates with PD-L1 upregulation and adverse outcomes in non-small cell lung cancer.

Pathology, research and practice

HSP與PD-L1表達正相關,預示較差預後,具生物標誌價值。

🌱 低

Role of primary protectors of plant cells in salinity tolerance: molecular mechanisms and adaptive strategies.

Plant signaling & behavior

概述植物在高鹽壓下的保護機制,闡述離子調控與抗氧化系統。

🥦 低

High internal phase emulsions stabilized by polyphenol-mediated Moringa seed protein for β-carotene encapsulation: Enhanced stability and bioaccessibility.

Food research international (Ottawa, Ont.)

Moringa種子蛋白與多酚穩定HIPE,提升β-胡蘿蔔素的載荷與生物利用度。

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