Gaming Disorder Research · 遊戲障礙研究文獻日報

Gambling Streams and Gambling Intentions: Testing via the Theory of Planned Behaviour.

Journal of gambling studies

觀賞老虎機與電競直播正向預測賭博意圖，但電玩直播則負相關，顯示內容類型對行為意圖具分流效應。

The Impact of Video Game Experience on Surgical Performance: A Systematic Review.

Journal of surgical education

電子遊戲經驗與腹腔鏡手術表現正相關，尤其在正式訓練前顯著，提示其可能作為非正式術前準備工具。

Exergaming Interventions for Preventing Falls and Injurious Falls in Older People: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

JMIR aging

互動運動遊戲可能降低老年人跌倒率，但異質性高，需標準化設計以提升實證力度。

[Not Available].

Salud publica de Mexico

墨西哥青少年與成人中，0.9%符合網路遊戲障礙診斷，該障礙與心理困擾、自殺行為及藥物使用顯著相關，支持IGDS9-SF在該文化背景下的效度。

Motivational Factors, Physical Activity Impacts, and Sociopsychological Effects of Pokémon GO in Players Over the Years: Scoping Review.

Journal of medical Internet research

寶可夢GO初期提升步數，但效果多為短暫，較久 sedentary、超重或老年人受益較為持久。

Association Between Esports Participation and Health: A Systematic Review and Meta-analysis.

Sports medicine - open

電競選手抑鬱程度較低，但非職業選手體脂率較高，且久坐、BMI與遊戲障礙呈正相關，顯示健康影響具雙重性。

Technology addiction as a predictor of visual problems in early adolescents: a multicentre case-control study.

Primary health care research & development

線上遊戲成癮與視力問題正相關，特別是在男性中較為顯著，支持將數位衛生納入學校與基層衛生預防。

Validation of the French version of Online Gambling Disorder Questionnaire.

L'Encephale

法語版OGD-Q展現優秀內部一致性與單一結構，並與IGD-20及負面情緒顯著相關，支持其在法語區臨床與研究使用。

Reactive granulomatous dermatitis as a paraneoplastic phenomenon.

Clinics in dermatology

間質性肉芽腫性皮膚炎可能為內部惡性腫瘤的早期皮膚表現，提醒皮膚科醫師警惕其作為體內疾病的指標。

Targeting IFN-I driven tertiary lymphoid structures halts B cell-mediated bone loss in periodontitis.

International journal of oral science

IFN-I訊號驅動的第三類淋巴結促進B細胞經由RANKL導致牙周骨吸收，其抑制可減緩骨損失，揭示新療法標靶。

The neural and physiological mechanisms of Animal-Assisted Interventions (AAI): A systematic review and integrated framework.

Comprehensive psychoneuroendocrinology

動物輔助干預經由增強前額葉-杏仁核連結、降低皮質醇及增加催產素來調節情緒與壓力，對ADHD與創傷後壓力症狀具潛在益處。

Shared and Unique Patterns of Dysregulated Dual Systems Between Adolescent Problematic Video Gaming and ADHD.

PsyCh journal

問題視訊遊戲與ADHD共享雙系統失衡機制，但獎賞敏感性與抑制控制在兩症中的關聯模式不同，提示共病評估需區分路徑。

Seeking pleasure or seeking compensation: a dual-pathway model of problematic social networks use.

Addictive behaviors reports

問題社交網路使用分為尋求愉悅（增加使用時間）與尋求補償（增加症狀嚴重度）兩條路徑，支持擴充I-PACE模型以涵蓋負向強化。

Effects of Children's Video Gaming Experience on Chinese Orthographic Processing and Its Neural Mechanisms.

Developmental science

動作類電子遊戲玩家在控制遊戲時間後，於中文正字處理任務中表現更佳，並展現更強視覺-工作記憶腦網路整合。

The association of psychological need dissatisfaction with problematic digital gaming: Mediating roles of EPOCH well-being and resilience in adolescents.

Acta psychologica

心理需求不滿透過降低EPOCH幸福感與韌性間接增加問題數位遊戲使用，支持自我決定理論在青少年遊戲行為中的適用性。

Neural correlates of appetitive learning and extinction in individuals with risky gaming use and gaming disorder.

Behavioural brain research

問題遊戲使用者對非成癮相關獎賞（如色情、金錢）的腦獎賞反應減弱，但在滅絕過程中顯示較高杏仁核激活，提示其對非遊戲獎賞敏感度降低與負向誘發過度反應。

Perceived physical literacy, self-reported physical activity, and sports video gaming among university students: a cross-sectional study.

Journal of exercise science and fitness

體育類電子遊戲參與與較高身體素養感、自主動機及中高強度運動量正相關，但一般電子遊戲則無此益處，支持類型區隔的重要性。

The Role of eHealth Literacy in Internet Gaming Disorder and Help-Seeking Among College Students.

Western journal of nursing research

較高電子健康素養與較低IGD症狀相關，並透過提升治療控制感間接促進求助意願，顯示其具預防與促進求助的雙重潛力。

Neural symphony of flow experience: Evidence for high-dimensional metastable dynamics.

NeuroImage

流動體驗中腦網路展現最高全域功能連結與動態維度，支持其為高維神經穩態過程，有助理解沉浸式遊戲的神經基礎。

Site-specific enrichment of highly sialylated N-glycans in an erythropoietin-hybrid Fc fusion protein.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

EPO-Fc融合蛋白在特定位點呈現高度唾液酸化，此結構特性與其延長血清半衰期直接相關，提供藥物設計結構基礎。

Pharmacotherapy for online behavioral addictions: a systematic review.

Future science OA

布齊opropion、SSRI與阿片受體拮抗劑在線上行為成癮中顯示初步療效，但樣本小與追蹤短限制證據強度，支持未來雙藥或聯心理治療研究。

Neural trajectories of gaming disorder accounting for psychopathology: Insights from the longitudinal ABCD study.

NeuroImage

發現獎賞處理從早期低激活（11-12歲）轉為過度激活（13-14歲），且焦慮與ADHD強化右島葉與遊戲障礙症狀的關聯，支持右島葉為GD的穩定神經標誌。

Novel transfersome-based vaccine delivery for red tilapia: Enhancing immunization against Francisella orientalis using bacteriocin from cell-free supernatants.

Fish & shellfish immunology

以菌素載體的轉移體納米疫苗顯著提升羅非魚對フランシセラ定向菌的免疫反應與存活率，且無明顯毒性，提供水產疫苗新策略。

Adolescents and loot boxes: a systematic review of behavioral mechanisms and problematic outcomes.

Addictive behaviors

loot box 參與透過認知偏差（如近錯誤）與習慣機制引導青少年類賭博行為，支持其作為遊戲內賭博化的潛在風險。

Integrated Multiomics Reveals Key Drivers and Immune Cell Phenotypes of Infrapopliteal Atherosclerosis and Calcification.

Annals of vascular surgery

HLA-B基因上調驅動下肢動脈粥樣硬化，並經IgD+ B細胞介導，提示免疫基因在血管病理中的新角色。

The use of virtual environments to prevent or treat behavioral addictions: A systematic review.

Journal of psychiatric research

VR/AR為基礎的干預在減少賭博與遊戲障礙渴望、時間及負面情緒方面顯示潛力，但劑量標準化研究仍不足。

A systematic review and meta-analysis of electroencephalographic evidence and applied methods to cue-reactivity and cue exposure. Part I: ERP.

Neuroscience and biobehavioral reviews

成癮個體對目標線索的LPP振幅顯著增高，效應值大，支持ERP為成癮神經敏感性的穩定標誌，但需標準化設計以提升比較性。

Pretransplant circulating cTfh17 and donor-reactive T follicular helper responses distinguish liver transplant recipients who develop ischemia-reperfusion injury and donor-specific antibody.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

移植前升高的cTfh17細胞可預測術後缺血再灌注傷害與抗體產生，揭示移植前免疫狀態與移植後結果之間的因果鏈。

An investigation into factors associated with adolescent internet gaming disorder: utilizing machine learning and path analysis model.

Journal of affective disorders

透過機器學習與路徑分析識別出 avatar identification 與 character attachment 為青少年網路遊戲障礙的新興風險因子，支持虛擬自我同一性在成癮發展中的角色。

Emotion regulation profiles moderate links between perceived interparental conflict, peer bullying victimization, and adolescent internet gaming disorder.

Addictive behaviors

高度認知重評與低抑壓的情緒調整模式能降低親子衝突與同儕欺凌對網路遊戲障礙的影響，支持情緒調整訓練具保護功能。

Frustration-related cognitive, motivational, and self-regulatory dysregulation in gaming disorder: roles of frustration intolerance, frustrative non-reward, and procrastination.

Addictive behaviors

挫折不耐受、非獎賞反應與拖延共同預測遊戲障礙診斷與嚴重度，支持挫折相關認知-動機-調節框架在GD中的適用性。

Beyond comorbidity: bidirectional association between sleep problems and internet gaming disorder and the mediating role of resilience and emotional problems: a three-wave cohort study among Chinese adolescents.

Journal of psychiatric research

證實睡眠問題與網路遊戲障礙具有顯著雙向縱向關聯，其中情緒問題介入男性路徑，彈性介入女性路徑，揭示性別特異的機制路徑。

Effects of social rewards on risky decision-making among individuals with internet gaming disorder.

Journal of behavior therapy and experimental psychiatry

IGD個體在社會獎賞（特別是遊戲相關）下做出更風險的決策，且其風險偏好與症狀嚴重度正相關，提示社會強化在GD決策失調中的角色。

Unraveling the dynamics among Internet gaming disorder, depression and emotion dysregulation in Chinese adolescents: A cross-lagged panel network analysis.

Addictive behaviors

憂鬱的情感成分為IGD、憂鬱與情緒失調網絡中的核心橋樑症狀，並證實症狀間存在自我強化迴路，支持以症狀網絡為基礎的精準干預。

IgD-λ multiple myeloma with hidden light chain on immunofixation electrophoresis: a clinical case.

Clinical chemistry and laboratory medicine

Neural representations of dynamical state and trait impulsivity in individuals at risk for internet gaming disorder.

Molecular psychiatry

衝動的狀態與特徵表現透過右中前額尾根與靜態功能連結在IGD高風險個體中可被區分，並顯示IGD透過腦連結間接影響特質衝動，支持其為神經行為連續體。

Longitudinal associations among posttraumatic stress symptoms, intolerance of uncertainty and internet gaming disorder symptoms among disaster-exposed adolescents.

Addictive behaviors

創傷後壓力症狀預測後續遊戲障礙增加，且此關係經無法容忍不確定性部分中介，支持在災害後介入中加入認知因素篩選。

Exploring the causal links among immune cell characteristics and prostatitis: a bidirectional two-sample Mendelian randomization study.

The aging male : the official journal of the International Society for the Study of the Aging Male

特定免疫細胞表型（如CD39+調節性T細胞）與前列腺炎風險存在因果關聯，支持免疫調整在前列腺疾病中的角色。

Immune-mediated pathways between red blood cell traits and prostate cancer: a causal relationship network based on Mendelian randomization evaluation.

The aging male : the official journal of the International Society for the Study of the Aging Male

紅血球特徵經樹突狀細胞上的HLA-DR或IgD+ B細胞介導前列腺癌風險，揭示造血-免疫系統交互作用在癌症病理中的新機制。

Blink rate self-regulation, tear volume and ocular symptoms in expert and naïve action video game players.

Clinical & experimental optometry

專業動作遊戲玩家在遊戲中顯著降低眨眼率（尤其在非動態場景），但未見淚量改變，提示其為適應性視覺策略而非乾眼標誌。

A nephritic puzzle: C3-dominant glomerulonephritis as a sentinel of hidden autoinflammatory disease.

Pediatric nephrology (Berlin, Germany)

C3占優勢的腎小球腎炎可能為隱匿性自體發熱疾病（如HIDS）的早期表現，提醒腎科醫師在常規免疫抑制失效時考慮IL-1β阻斷療法。