今日文獻聚焦於食物厭惡的多維度機制,特別是神經科學與心理因素在化療、暴食症與ARFID中的作用,顯示出從分子層面(GDF15, insula)到行為干預(好奇心誘發、情緒社會化)的整體趨勢。
Trends in neurosciences · Linking sensory experience to bodily states in the insular cortex.
此篇論文闡述島葉皮質如何整合味覺、內臟與情感資訊來建立條件化味覺嫌惡,為理解食物厭惡的學習與記憶提供核心神經科學框架。
EBioMedicine · Early pregnancy GDF15 trajectories and their association with normal gestation, pregnancy loss, and hyperemesis gravidarum.
GDF15在早孕呈sigmoidal上升模式,妊娠劇吐患者在診斷時已達高平台,而正常孕媽則於第8週後下降,顯示其具時序特異性作為HB的潛在生物標誌。
Appetite · Odor-elicited anxiety-to-eat is heightened and independent of odor liking, intensity, and identification in anorexia nervosa.
神經性厭食症患者對高低能量密度食物氣味皆產生顯著增強的進食焦慮,此現象不由氣味辨識、強度或喜好所駕馭,提示其為獨立的條件化厭惡機制。
Appetite · Seeking answers, trying insects: Induced curiosity as a catalyst for novel food consumption.
透過未解謎題誘發好奇心可增加昆蟲麵食點心的實際攝取量(約5%一份),此效應受食物恐新症抑制,且男性受益更顯著,女性則有負向直接效應。
Obesity (Silver Spring, Md.) · Eating Behavior Latent Profiles and Their Associations With Body Composition in Early Childhood: The CORALS Cohort.
識別出四種飲食類別(控制型、熱情型、典型型、迴避型),其中控制型飲食者在男孩與無脂肪質量呈正相關,女孩則負相關,提示性別特異的飲食調節機制。
Appetite · Feeding the mood: The role of parental emotion socialization in children's avoidance-oriented behaviors observed during mealtimes.
父母在非偏好餐時表現出更多支持性與非支持性情緒反應,而這兩種極端皆與孩子較多樣化的食物回避與抱怨行為相關;相反,和諧的親子情緒氣候則為保護因子。
European eating disorders review : the journal of the Eating Disorders Association · Associations Between Avoidant/Restrictive Food Intake Disorder Dimensions and Obsessive-Compulsive Symptomatology.
ARFID 的三個核心維度(感官敏感、低食慾、害怕後果)皆與OCD症狀顯著相關,調整憂鬱焦慮後減弱但仍存,且關聯模式在男女間有顯著差異。
Clinical therapeutics · Adverse Drug Events Associated With Six Classes of Glaucoma Medications: A Retrospective Pharmacovigilance Study Using Real-World Data From The FAERS Database.
在青光眼用藥中,碳酸酐酶抑制劑顯著聯繫到味覺改變(dysgeusia),提示即使非腫瘤藥物也可能經由味覺通路引發食物厭惡或營養攝取問題。
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
在接受化療的患者中,食物恐新症與報告一般味覺改變正相關,而獎賞敏感性則與幻味/異味和噁心呈負相關,提示人格特質可預測味覺毒性反應的個體差異。
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
在妊娠劇吐患者與健康對照中,血清BDNF水平在第一及第二孕期無顯著差異,且孕期內變化無群組間差異,提示BDNF可能不直接參與妊娠劇吐病理機制。
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
母體幽門桿菌感染顯著增加妊娠劇吐風險(RR 5.57),提示根除療法或預防策略或可減輕HB負擔,但需注意觀察研究的限制。
Surgical pathology clinics
EoE的診斷不應僅依賴黏膜嗜酸性粒細胞計數,須整合黏膜外樣、斑紋、溝槽等全組織圖像,才能理解其慢性免疫介導性病理與臨床表現如食物回避。
Case reports in women's health
一例嚴重妊娠劇吐引發的自發性縱隔氣腔、脊髓腔氣腔及廣泛皮下氣腫病例,提示劇嘔所導致的壓力損傷可波及非預期解剖結構,需警惕異常胸腔或頸部症狀。
Food research international (Ottawa, Ont.)
AI在植物性肉類開發中可優化感官特性、營養與接受度,透過預測與設計降低試誤成本,並有潛力經由改善感官體驗間接降低新穎食品的恐新反應。