今日共收錄 5 篇前額葉皮質相關文獻,涵蓋多個研究領域。
Molecular psychiatry · Anxiety influences the addictive feature of non-suicidal self-injury behavior via somatic symptom in adolescents with major depressive disorder.
研究發現焦慮透過軀體症狀驅動重鬱症青少年非自殺性自傷(NSSI)的成癮特徵。針對左側背外側前額葉皮質的加速間歇性θ短陣發刺激能有效干預此路徑,為臨床治療NSSI成癮提供新方向。
Psychiatry research · Symptom trajectories and treatment outcomes following a five-day accelerated intermittent-theta burst stimulation protocol for treatment-resistant depression: A naturalistic study in a real-world setting.
評估在無神經導航下,於真實世界臨床環境中實施五天高頻率加速間歇性θ短陣發刺激治療難治型憂鬱症的可行性。結果顯示該協議具可行性且能適度減輕症狀,但個體反應差異大,凸顯後續追蹤與個人化策略的需求。
Journal of nutritional science · APOE-ε4 moderates the association between diet quality and executive function in middle-aged women at increased risk for Alzheimer's disease.
探討飲食品質與阿茲海默症遺傳風險因子對中年女性執行功能的交互影響。研究發現良好的飲食品質僅在非APOE-ε4攜帶者中與較佳的整體執行功能及工作記憶顯著相關,提示攜帶者可能需要更高的飲食干预門檻才能產生認知益處。
Metabolism: clinical and experimental · The effects of acute ketone monoester supplementation on brain insulin responsiveness and cognitive performance: Results of a randomized, double-blind, placebo-controlled crossover trial in older men with overweight.
隨機雙盲交叉試驗顯示,急性酮酯補充能快速誘發營養性酮症,並逆轉包含前額葉在內之腦區對胰島素的異常血流反應。此干預雖未改善記憶或執行功能,但能微幅提升老年人的注意力與精神運動速度。
Psychology of sport and exercise · Age-Dependent Cross-Level Gradients of Exercise-Associated Advantages in Behavioural, Latent, and Neural Efficiency.
結合行為、潛在與神經效率指標,探討長期運動習慣對不同年齡層執行功能的影響。研究發現運動帶來的認知優勢具備任務特異性與年齡差異,在老年人中主要表現於行為與潛在層面,為運動處方提供精準化依據。