近期文獻顯示新興介入如Ketamine、rTMS與神經調節技術在急性憂鬱及自殺風險治療上展現迅速效益，同時呼籲更寬鬆的試驗設計以納入真實世界人群，以及對症狀聚類與指標的系統性探索
Depression and anxiety · High Dose Vitamin B6 Reduces Depression Symptoms
高劑量維生素B6顯著降低抑鬱症狀，具備極佳臨床效果。
Journal of affective disorders · Connectome-based Graph Metrics Predict Electroconvulsive Therapy Response in Adults with Depression
基於大腦連接圖的圖論結構可預測ECT治療後緩解。
Journal of affective disorders · Investigating the effects of antidepressants on measures of insulin resistance in major depressive disorder: A systematic review
特定抗憂鬱藥物會影響胰島素抵抗，提供代謝視角。
Journal of affective disorders · Latent Class Modeling of Repetitive Transcranial Magnetic Stimulation Response Trajectories in Treatment-Resistant Depression
利用LCMM分類rTMS治療反應路徑，識別高風險非應答者。
Journal of affective disorders · Serum brain-derived neurotrophic factor following oral esketamine in treatment-resistant depression: Results from a randomized placebo-controlled trial
口服Esketamine未提升BDNF，揭示生理門檻限制。
Depression and anxiety · High Dose Vitamin B6 Reduces Depression Symptoms
維生素B6可顯著降低抑鬱症狀，具備高度可操作性。
Journal of affective disorders · Pharmacologic and expectancy effects in depression: Associations with inter-network resting-state connectivity
探討交疊網路連接性如何預測藥物與安慰劑反應。
Journal of affective disorders · Prevalence and outcomes of real-world bipolar depression patients underrepresented in guideline RCTs
真實世界樣本顯示患者多屬指標下限，需擴大試驗入組。
Journal of affective disorders
Ketamine快速減少自殺住院患者的心理痛苦。
Journal of affective disorders
輔助心理治療提升esketamine治療效果。
Journal of affective disorders
不同評估工具導致反應差異，需多指標檢視。
Psychological medicine
symptom clusters可預測治療結果差異。
Depression and anxiety
高劑量維生素B6顯著降低抑鬱症狀。
Journal of affective disorders
口服Esketamine未顯著提升BDNF。
Journal of affective disorders
藥物組合顯著提升精神病性抑鬱症臨床改善。
Journal of affective disorders
不同量表影響Ketamine治療解讀。