今日文獻聚焦於BPD的生理機制(如HPA軸功能)、共病特質(特別是易傷型自戀)、診斷障礙(尤其是青少年)及新興治療方法(如非侵入性腦刺激),顯示從基礎神經內分泌到臨床實踐與服務體系的多維度研究趨勢。
Personality and mental health · Vulnerable Narcissism in Borderline Personality Disorder: Impact on Emotion Dysregulation, Identity Disturbance, and Rejection Sensitivity in Psychiatric Inpatients.
發現易傷型自戀與BPD共病時,會顯著加重情緒失調、身份擾亂和拒絕敏感度,並增加自殺未遂與創傷暴露,提示需早期辨識以進行針對性干預。
Personality and mental health · When Guidelines Are Not Enough: Clinician Hesitation to Diagnose Borderline Personality Disorder in Adolescents as a Barrier to Timely Evidence-Based Care.
儘管指南支持青少年BPD診斷,醫師仍因污名化或過早診斷之懼而猶豫,導致青少年獲得零散照護而非根本治療。
Journal of affective disorders · Mineralocorticoid receptor stimulation effects on stress-induced cortisol and alpha-amylase in female patients with borderline personality disorder and healthy controls: A randomized placebo-controlled experimental study.
BPD女性在社會壓力下皮質醇反應鈍化,但受體刺激後兩組反應趨於一致,顯示該鈍化非主要由過度的MR中介負回饋造成。
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · Advances in non-invasive brain stimulation for borderline personality disorder: clinical targets and future directions - an updated narrative review.
右側DLPFC刺激或有助於衝動控制,左側DLPFC改善情緒調節,右側VLFC可能緩解拒絕敏感,NIBS結合心理治療可行但加成效應尚需證實。
World psychiatry : official journal of the World Psychiatric Association (WPA) · Network analysis of the genetic relationships between twenty psychiatric and substance use disorders.
BPD的遺傳風險與自殺行為、雙極情緒失調、內化及外化障礙、飲食失調有廣泛關聯,顯示其在精神病理遺傳網絡中的橋接角色。
Brain, behavior, & immunity - health
包含BPD在內的產期精神障礙與高血壓、早產、胎兒生長異常等不良產科及新生兒結果相關,但證據多來自觀察研究且異質性高。