今日文獻以自閉症譜系障礙的微環境調控、神經影像診斷工具開發及執行功能長期追蹤為重點,同時呈現多項與共病症相關的重要研究,突顯ASD臨照管理的複雜性與跨領域整合需求。
Med (New York, N.Y.) · Microenvironment dysregulation in autism spectrum disorder: Immune, epigenetic, synaptic, and gut-brain mechanisms.
研究揭示ASD涉及多系統微環境失衡,整合免疫、表觀遺傳、突觸功能及腸腸軸異常,為未來精準治療提供新方向。
Imaging neuroscience (Cambridge, Mass.) · Naturalistic movie viewing is an effective functional localizer of the fusiform face area in adolescents with and without autism.
開發基於自然刺激的神經影像新方法,能有效定位自閉症青少年梭狀面孔區域,提升臨床診斷準確性。
Journal of child psychology and psychiatry, and allied disciplines · Executive function challenges persist into young adulthood and predict mental health outcomes in autism.
長期研究證實ASD患者執行功能障礙持續至成年早期,且顯著影響心理健康結果,強調早期介入的重要性。
Autism : the international journal of research and practice · A 5-Year Update of Conflicts of Interest in Autism Intervention Research in Applied Behavior Analysis Journals.
研究發現應用行為分析(ABA)研究中利益衝突普遍存在,影響研究結果的客觀性,呼籲提高研究透明度。
International journal of language & communication disorders · Investigation of Swallowing Performance and Family Impact in Children With Speech and Language Delay.
揭示語言延遲兒童常伴隨吞嚥障礙,並顯著影響家庭生活品質,呼籲跨專業團隊合作。
Journal of autism and developmental disorders · The Roles of Different Executive Functioning Skills in Early Mathematics Ability of Preschoolers With Autism.
研究發現工作記憶、認知靈活性和抑制控制三種執行功能對自閉症學齡前兒童數學能力有不同影響。
BMJ case reports · Delayed diagnosis of congenital duodenal obstruction in early adolescence in a patient with Down syndrome and autism spectrum disorder.
報告一例Down綜合合併自閉症患者在青少年期才確診先天性十二指腸阻塞的案例,強調多重障礙診斷的挑戰。
Journal of autism and developmental disorders · Co-occurring Psychiatric Symptoms in Verbal, School-Aged Children With Autism Spectrum Disorder and at Least Average IQ.
研究發現高功能自閉症學齡兒童普遍存在共病精神症狀,需專業評估與整合干預。
Scientific reports
開發基於功能連接性的深度學習模型,提高自閉症診斷準確性
The American journal of occupational therapy : official publication of the American Occupational Therapy Association
評估遠程健康模式下的感官統合介入可行性,為自閉症治療提供新選擇
Genome medicine
鑑定CHD3相關自閉症的表型特徵,有助於精準診斷
Genetics
研究FOXP基因在感覺神經發育中的作用,有助於理解自閉症病理機制
Journal of neuro-oncology
研究兒童腦瘤存活者神經行為結果,部分患者表現出自閉症特徵
American journal of medical genetics. Part A
報告HUWE1基因突變導致的神經發育障礙臨床表型,提供臨床評估建議