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Therapist-guided and self-guided internet-based behavioural activation versus treatment as usual for adolescents with depression: randomised controlled trial with economic evaluation.
BMJ mental health · Therapist-guided and self-guided internet-based behavioural activation versus treatment as usual for adolescents with depression: randomised controlled trial with economic evaluation.
治療師指導的網路行為激活療法在減輕青少年輕中度憂鬱症狀顯著優於常規治療,自我指導版雖無顯著差異,但兩組皆達臨床改善門檻,具高成本效益與推廣潛力。
P13-17歲,輕中度重度抑鬱障礙(MDD)青少年,n=219
I10週療師指導或自我指導網路行為激活療法(I-BA),含青少年和家長模組
C常規治療(TAU)
O3個月追蹤時CDRS-R分數平均下降:療師指導組17.0、自我指導組16.0、TAU組11.6;兩I-BA組皆低於臨床切口,療師指導組優於TAU(p=0.048),但未達預先設定的六點臨床重要差異
Suicidal Ideation Across the Lifespan Among Commercially Insured Outpatients: Retrospective Cohort Study.
JMIR mental health · Suicidal Ideation Across the Lifespan Among Commercially Insured Outpatients: Retrospective Cohort Study.
在全美商業醫保門診青少年(13-17歲)中,近三分之一(32.8%)報告過自殺念念,非二元性別青少年風險最高(37.5%),凸顯此群體為自殺防治的緊急優先對象。
P商業醫保門診患者,年齡6-64歲,焦點於青少年亞群(13-17歲,n=6426)
I無(觀察性研究)
C按年齡、性別、地理與社會脆弱度分組比較自殺念念(SI) prevalence
O青少年SI prevalence 32.8%,幾乎每日SI達4.8%;非二元性別群體SI達37.5%,顯著高於其他群體;SI與社會脆弱度正相關(p<.001)
Reciprocal associations between parent-child relationships and adolescent depressive symptoms: The longitudinal mediation role of insomnia and sex differences.
European child & adolescent psychiatry · Reciprocal associations between parent-child relationships and adolescent depressive symptoms: The longitudinal mediation role of insomnia and sex differences.
父親-子女關係與青少年憂鬱症狀存在顯著雙向負向關聯,失眠部分中介此關係,而母親-子女關係則無顯著關聯,凸顯父親角色在憂鬱症發展中的獨特影響。
P中國青少年,基線平均年齡13.0歲,n=939,63.7%男生
I無(縱隊觀察)
C父親-子女 vs 母親-子女關係對憂鬱症狀的交叉滯後影響
O父親-子女關係與後續憂鬱症狀顯著負相關(β=-0.14, p<0.01);失眠中介父親-子女(β=-0.10, p<0.001)與母親-子女(β=-0.05, p=0.01)關係對憂鬱症的影響
Effects of the Super Skills for Life Program on Depression and Anxiety Symptoms in Children and Adolescents: A Systematic Review and Meta-Analysis.
Clinical child and family psychology review · Effects of the Super Skills for Life Program on Depression and Anxiety Symptoms in Children and Adolescents: A Systematic Review and Meta-Analysis.
Super Skills for Life(SSL)跨診斷介入顯著降低青少年焦慮與憂鬱症狀(效應大小g=0.36–0.57),效果穩定且在兒童中較青少年更佳,支持其作為早期預防的有效工具。
P兒童與青少年(年齡未具體說明,但含青少年樣本),患有焦慮與/或憂鬱症狀
ISuper Skills for Life (SSL) 程式
C非作為對照組或等待名單
O從前測到後測的症狀減少效應大小g=0.343–0.591;對照組比較g=0.360–0.566;效果在隨訪中多穩定(除情緒問題外),兒童效果優於青少年
Impact of Transdiagnostic Brief Behavioral Therapy on Suicide Reduction for Depressed Hispanic/Latine Youth.
Archives of suicide research : official journal of the International Academy for Suicide Research · Impact of Transdiagnostic Brief Behavioral Therapy on Suicide Reduction for Depressed Hispanic/Latine Youth.
對於有憂鬱症的西班牙裔/拉丁裔青少年,簡短行為療法(BBT)顯著降低自殺念念與行為,顯示跨診斷介入在特定文化與臨床亞群中具備防治自殺的潛力。
P8.0–16.9歲,臨床顯著憂鬱症且為西班牙裔/拉丁裔青少年,n=163(子樣本)
I簡短行為療法(BBT)
C社區轉介協助(ARC)
O種族、憂鬱症與治療的三-way交互作用顯著:BBT組在憂鬱症西班牙裔/拉丁裔青少年中相較於ARC組自殺念念顯著減少(週16)
📚其他值得關注的文獻
Impacts of vaping on children and young people: a systematic review.
Archives of disease in childhood
電子煙使用與青少年憂鬱、焦慮、恐慌症等精神健康問題顯著相關,尤其在較年輕青少年中風險更高,證實其為可避免的心理健康危害因子。
Resting frontal alpha asymmetry is associated with rejection sensitivity beyond anxiety and depressive symptoms in young adults.
Biological psychology
靜息前額Alpha asymmetries與拒絕敏感度顯著正相關,獨立於焦慮與憂鬱症狀,提供潛在神經生物標記用於理解青少年社會情感脆弱性。
Editorial: The BEAM Study: Micronutrients for Teen Irritability.
Journal of the American Academy of Child and Adolescent Psychiatry
編輯部落文,介紹BEAM研究聚焦微量營養素對青少年易怒症狀的影響,尚無實證結果。
Can fluoxetine's diminished efficacy in pediatric depression be explained by study sites, baseline severity, age, and psychological interventions? A secondary exploratory meta-regression.
Journal of psychiatric research
氟西汀在兒童青少年憂鬱症療效下降無法被試驗特徵(中心數、年齡、基線嚴重度、心理介入)解釋,提示效應變化可能來自未測試變數或出版偏誤。
Towards cultural validation of the revised children's anxiety and depression scale in Karnataka, India: Think aloud interviews among 13-17 year olds.
PloS one
RCADS-47在印度青少年中存在文化語意不適合項(47題中14題 problematic),尤其強迫症子量表,提示需文化適應修改才能準確量測印度青少年憂鬱焦慮。
Physical exercise and risk of common mental disorders among higher education students: A national prospective study.
PloS one
較低身體活動水準顯著增加大學生後續罹患憂鬱或廣焦慮症風險,尤其男性與18-24歲群體效應更明顯,支持運動作為預防憂鬱症的生活方式干預。
Eating disorders, depression, and anxiety among East Asian American young adults in the United States: patterns of mental health service use.
Ethnicity & health
東亞裔美年輕成年人中,憂鬱/焦慮與進食 disorder 共病增加心理諮商使用機會,但同時患兩者者反而較少使用服務,提示共病群體可能面臨更大治療障礙。
Empathy and suicide-related stigma among emerging adults: A structural equation modeling study.
Death studies
在秘魯大學生中,共情能力與自殺相關污名(特別是隔離/抑鬱信念)顯著負相關,支持共情訓練可能降低自殺防治中的求助障礙。
Mental health distress among undergraduate nursing students in Egypt: associations with self-concealment, alexithymia, and personality traits in a cross-sectional study.
BMC nursing
埃及護理學生心理困窘普遍,自我隱藏與阿萊西米亞顯著預測憂鬱、焦慮與壓力,解釋近一半變異,提示情感處理能力是心理健康關鍵因子。
Multinational prevalence and burden of paediatric disorders of gut-brain interaction: results of the Rome Foundation paediatric global study.
Gut
腦腸互動障礙在全球兒童青少年中高發(28%),並與焦慮憂鬱顯著相關,提示消化道症狀可能是青少年內化問題的身體表現或共病。
Bridging brain structures and adolescent depression and anxiety symptoms: A symptom-oriented approach.
Journal of affective disorders
左/右蒼白核體積與青少年憂鬱症狀結合度最高,左誘核體積與焦慮症狀結合度最高,證明基底神經節在青少年內化症狀中的神經生物學關鍵角色。
Baseline Diet Quality Indicators and Six-Month Changes in Iron and Vitamin A Biomarkers among Rural Ghanaian Adolescents: A Secondary Analysis of the Ten2Twenty-Ghana Trial.
The American journal of clinical nutrition
在加納農村青少女中,整體飲食品質分數與鐵維生素A生物標記變化關聯有限,未顯著影響貧血或維生素A缺乏風險,提示現行飲食品質指標在低資源環境對微量營養素敏感度不足。
The effects of fitspiration TikTok content on body image and mood among young adult women in the U.S.
Body image
觀看TikTok fitspiration內容導致年輕女性社會比較、外觀焦慮與悲傷增加,尤其在已有外觀擔憂或低憂鬱症狀者中效應更明顯,警示社交媒體內容對身體形象與情緒的即時負面影響。
Adolescents' Preferences, Experiences, and Views of 2 Online Programs for Anxiety and Depressive Symptoms: Qualitative Interview Study.
JMIR pediatrics and parenting
英國青少年偏好互動、視覺吸引力強且文化相關的數位心理健康介入,強調年齡適切性與透明度是參與與感受有用性的關鍵,為設計青少年友善數位療法提供實質指引。
Perioperative Nursing Care of a School-Age Child With Lung Adenocarcinoma Based on the Family-Centered Empowerment Model and Enhanced Recovery After Surgery: A Case Report.
Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
一例7歲男童肺腺癌手術案例顯示,將家庭中心賦能模式與加速康復理念整合於護理路徑中,可安全促進身體康復、學校復學並減少父母焦憂,雖為個案但具臨床啟發值。
Prevalence, Phenotypic Correlates and Predictive Factors of Catatonia in Adolescents With Autism Spectrum Disorder.
Journal of intellectual disability research : JIDR
自閉症青少年中21.5%併發緊縮症,女性、自閉症嚴重度、憂鬱症與分離焦慮為顯著危險因子,提示需在ASD評估中常規篩檢緊縮症,尤其是高風險亞群。
High school coping patterns and emerging adult mental health across COVID-19: A latent profile transition analysis.
Child development
高中階段平衡或調節型應對方式(如問題解決、尋求支持)與後續疫情期間較少憂鬱症狀相關,而迴避或自我導向應對則風險更高,顯示早期應對風格為疫情韌性的重要預測因子。
Joint Latent Profile Analysis of BIS/BAS and Self-Control Systems in Gender Differences of Internet Gaming Disorder Among Chinese University Students: The Mediating Role of Anxiety and Depression in a
Psychology research and behavior management
在中國大學生中,網路遊戲 disorder 之性別差異部分可由焦慮與憂鬱的中介作用解釋:男性中兩者皆具中介效應,女性中僅焦慮具顯著中介,提示情緒困擾在遊戲成癮中的性別特異性路徑。
Low-FODMAP diet for pediatric patients with disorders of gut-brain interaction: A systematic review and meta-analysis.
JPEN. Journal of parenteral and enteral nutrition
低FODMAP飲食在兒童腸腸互動障礙中對腹痛有顯著改善效應(特別是IBS),但對功能性腹痛證據不足,整體滿意度在IBS組較高,支持其作為腸症狀一線飲食療法的潛力。
More Screens for Teens? The Incremental Value of Screening for Depression, Suicidality, and Anxiety in Pediatric Primary Care.
The Journal of pediatrics
在兒童初級照護中,將憂鬱篩檢擴充至焦慮與自殺風險篩檢,可每13名青少年額外發現1名陽性案例,證明多重篩檢的邊際價值顯著,支持整合式心理健康評估。
Social class identity and mental health in emerging adults: The mediating roles of greenspace and spatial social networks.
Acta psychologica
社會階級認同與新興成年人憂鬱症狀及心理困窘顯著負相關,此關係經空間社交網路部分中介,綠空間利用則僅對憂鬱有小幅中介效應,支持社會結構與環境因素共同塑造心理健康。
Associations between community engagement, human flourishing, and mental illness symptoms among college students.
PLOS mental health
大學生參與家庭、同儕、學校與教會社群顯著正相關於個人蓬勃發展,進而間接降低憂鬱與焦慮症狀,尤其同儕參與效應最強,支持社會連結作為心理健康保護因子。
Risk Factors for Non-Suicidal Self-Injury in Adolescents: Evidence from a Meta-Analysis of 18 Longitudinal Studies.
Issues in mental health nursing
青少年非自殺性自傷的主要預測因子包括既往自傷史(OR=2.34)、自殺念念/行為(OR=2.35)、女性(OR=1.59)、憂鬱症狀(OR=1.21)與同儕受害(OR=1.08),憂鬱症為核心危險因子之一。
Fine-tuning large language models for detecting negative self-referential language in smartphone text among youth with depression.
Journal of psychopathology and clinical science
微調大型語言模型(如GPT-4-mini)能夠從青少年智慧型手機文字中偵測負自我參照語言(F1=.84),此語言預測次日情緒惡化及一週後憂鬱復發風險增加,顯示被動數位監測在憂鬱症追蹤中的潛力。
Sleep duration and sleep problems in non-Hispanic Black adults: a cross-sectional study of the 2015-2020 National Health and Nutritional Examination Survey.
Ethnicity & health
非西班牙裔黑人成年人中,睡眠問題與較短睡眠時長顯著相關,並與男性失業、 depressivesymptoms 及慢性疾病正相關,提示種族健康不公在睡眠健康中的體現,但此研究聚焦成年人而非青少年。
Associations of mental health with subsequent weight development during a 4-year follow-up in adolescence.
Pediatric research
青少年憂鬱症狀與基線BMI較高但隨時間BMI增加幅度較小相關,而自尊心高則與基線BMI低但BMI增加幅度較大相關,顯示心理健康塑造青少年體重發展軌跡的雙向機制。
Association of the COVID-19 lockdown and Generalized Anxiety Disorder-7 (GAD-7) in Korean adolescents.
Medicine
韓國青少年在2020年COVID-19封城期間,焦慮(GAD-7≥10) prevalence 11.2%,嚴重壓力(OR=10.01)與憂鬱(OR=2.78)為焦慮的極強預測因子,凸顯疫情壓力與內化症狀的嚴重交互。
Validation of the multi-dimensional scale for Anti-Social Behavior in a higher education setting (ASB) in a sample of Afghan students.
BMC psychology
阿富汗大學生樣本中,反社會行為量表(ASB)展現良好兩因素結構效度與信度,並與憂鬱、焦慮、壓力顯著相關,支持其在不同文化背景下作為行為與心理健康相關測量工具的潛力。
Restless-Leg Syndrome Among Adolescents: Impact on Sleep Quality, Mood, and Academic Performance.
Behavioral sleep medicine
近三成青少年經歷不安腿症狀,顯著關聯較差睡眠質量、增加日間嗜睡、提升憂鬱焦慮壓力風險(OR>1.5)並降低學業成績(尤其科目與英語),提示RLS為青少年身心功能的重要可治療共病。
Does intervening to improve early academic adversity impact later mental health during adolescence? A population-based linked data modelling study in Wales.
BMJ open
威爾士顯示,6年級學業逆境(如成績、出席、師生比)與青少年焦慮憂鬱診斷風險顯著正相關,早期介入如Sure Start與免費餐飲可緩解此風險,但效應規模有限,支持教育與心理健康的跨部門預防佈局。
Antipsychotic medication and the prevention of psychiatric emergencies in difficult-to-treat adolescent depression.
Journal of affective disorders
在難治青少年憂鬱症中,使用抗精神病藥物(非第一線)反而增加精神科急診風險(HR=1.59),而非減少,不支持其作為預防精神科急診的保護策略,提示用藥需謹慎。
Association between stroke history, depression, and suicidal ideation: National health and nutrition examination survey, 2011-2018.
Clinical neurology and neurosurgery
中風病史與憂鬱症併發時,自殺念念風險顯著增加(AOR=1.86),提示神血管事件可能透過神經生物或社會機制放大內化症狀的自殺風險,但此樣本以中老年為主,青少年資料有限。
Co-developmental trajectories of bedtime procrastination and sleep disturbance in adolescents: Predictors and mental health implications.
Sleep medicine
青少年中存在兩種就寝拖延與睡眠擾動的共同發展軌跡:低風險群(85.1%)穩定低水準,而高風險群(14.9%)隨時間惡化,後者顯著關聯較高廣泛性焦慮與憂鬱,提示睡眠行為可作為早期預警指標。
EmotionaL and Language Recovery in Aphasia (ELLA): Codesigning and Proof-of-Concept Testing a Novel Intervention.
American journal of speech-language pathology
雖為失語症介入,但ELLA結合語言與心理療法(SFBT)顯示在改善溝通參與方面有潛力,提示跨域療法模式可啟發青少年憂鬱症的整合式介入設計,但與青少年憂鬱無直接關聯。
Seasonal differences in depressive affect, worry-related sleep disturbance, and low energy among UK young people.
PloS one
英國16-24歲青少年在冬季顯著較高憂鬱情感、擔憂相關睡眠擾動與低能量,雖效應量小(0.08 index points),但提醒季節性情緒波動在青少年群體中的存在,支持動態監測與季節性介入的必要性。
Examining Pubertal and Cognitive Differences in Adolescent Depressive Symptoms Using Drift Diffusion Modeling.
Research on child and adolescent psychopathology
早期青春期發育與較高決策邊界分離(反映謹慎決策)交互作用後,關聯較高青少年憂鬱症狀,提示認知謹慎與生物發育時機共同塑造早期青少年憂鬱風險,提供跨層次機制見解。
Cumulative Risks and Trajectories of Psychological Maladjustment in Chinese Adolescents: The Dynamic Mediating Role of Self-Esteem.
Journal of youth and adolescence
中國青少年中,家庭與學校累積風險透過自尊心軌跡部分中介影響憂鬱症狀與孤獨軌跡,家庭風險效應更大,支持自尊心為發展性心理健康的關鍵中介變數,強調早期環境與內在資源的互動。
Depression and Distress in Pediatric Type 1 Diabetes: A Latin American Multicenter Study.
Endocrine connections
拉丁美洲類1型糖尿病青少年中,過半(52%)有憂鬱症狀,超過四分之一(26.6%)有糖尿病相關困擾,兩者共병與較高HbA1c及較低社經地位顯著相關,提示慢性疾病管理需整合心理健康評估。
Variability in daily stressors and depressed mood in the context of chronic HIV stressors.
Journal of affective disorders
在HIV感染的年輕男男性行為者中,日常壓力與當日憂鬱情緒水準及其變異度顯著正相關,但慢性HIV壓力反而減弱此關聯,提示適應性應對或壓力反應疲勞可能調節壓力-情緒連結,提醒特殊人群的心理模型複雜性。
The long run: Fitness during childhood and adolescence and its association with adult depression.
Journal of affective disorders
兒童青少年期心肺耐力(1.6公里跑速)與成年後憂鬱風險呈負相關(尤其女性HR=0.80),肌肉適能關聯較弱,支持早期體能活動為成年憂鬱症的長期保護因子,但因果關係需進一步驗證。
Specific, Replicable Behavioral and Neural Correlates of Sensory Over-Responsivity in Childhood.
Journal of the American Academy of Child and Adolescent Psychiatry
感官過敏在兒童中與自閉症特徵、焦慮症狀顯著正相關,且伴隨 cingulo-parietal 網絡與雙側 caudate 核心功能連結降低,此神經模式具高度可重現性,提示感官處理異常可能是青少年內化症狀的共享神經底礎。