今日ADHD文獻聚焦於個別化治療策略,突顯基因與表型對藥物反應的影響(如CYP2D6與atomoxetine)、視覺輔助對敘事能力的促進效應,以及共病DMDD對治療軌跡的顯著影響。親職訓練與情緒調節的計算模型也呈現新興研究方向,強調需針對特定族群調整介入策略。
Journal of child and adolescent psychopharmacology · Association of Atomoxetine Discontinuation Patterns with CYP2D6 Phenotype in Children and Adolescents with Attention Deficit Hyperactivity Disorder.
研究發現正常/超快代謝型者較可能因療效不足停藥,而代謝力降低者較因毒性反應停藥,強調CYP2D6基因型應指導Atomoxetine起始劑量與監測,具高臨床實用性。
Research on child and adolescent psychopathology · A Picture is Worth How Many Words? The Impact of Visual Cues on the Story Retelling of Children with and without ADHD.
在有視覺故事提示條件下,ADHD兒童的敘事完整性與連貫性顯著提升,效果優於常規組,支持視覺輔助作為語言功能評估與介入的重要工具。
Journal of child and adolescent psychopharmacology · Disruptive Mood Dysregulation Disorder and Its Association with Treatment Trajectories and Outcomes in Youth with Attention-Deficit/Hyperactivity Disorder and Internalizing Disorders.
合併DMDD的ADHD青少年更可能使用較多藥物,尤其轉向非興奮劑(RR 1.73),且即使使用興奮劑也仍較少發生不良事件,提示共病情緒失調需更謹慎的藥物選擇與監測。
Journal of attention disorders · A Systematic and Explorative Literature Review Investigating Parent Training Interventions For Parents with ADHD.
現有研究雖少,但顯示針對ADHD父母的親職訓練(如治療父母ADHD或調整課程)可提升正向育兒技能,質化分析提供具體適應策略,凸顯個別化需求。
Journal of child and adolescent psychopharmacology · Prediction Gone Awry: A Computational Framework for Emotion Dysregulation Across Autism and Attention-Deficit/Hyperactivity Disorder.
理論框架提出ADHD可能源於預期過弱與增益控制不穩定,導致情緒反應波動大;自閉症則可能是驚訝訊號過度被信賴與預期更新遲緩共存,提供跨診斷的機制性解釋。